Journal article

Publication year: 2020

Journal: Scientific Reports

Volume number: 10

Issue number: 1

ISSN: 2045-2322

Open access status: Gold

DOI Link: https://doi.org/10.1038/s41598-020-58910-x

Publisher: Nature Research

Abstract: 
Pregnant patients undergoing minimally-invasive foetoscopic surgery for foetal spina bifida have a need to be subjected to advanced haemodynamic monitoring. This observational study compares cardiac output as measured by transpulmonary thermodilution monitoring with the results of non-invasive estimated continuous cardiac output monitoring. Transpulmonary thermodilution-based pulse contour analysis was performed for usual anaesthetic care, while non-invasive estimated continuous cardiac output monitoring data were additionally recorded. Thirty-five patients were enrolled, resulting in 199 measurement time points. Cardiac output measurements of the non-invasive estimated continuous cardiac output monitoring showed a weak correlation with the corresponding thermodilution measurements (correlation coefficient: 0.44, R-2: 0.19; non-invasive estimated continuous cardiac output: 7.4 [6.2-8.1]; thermodilution cardiac output: 8.9 [7.8-9.8]; p <= 0.001), while cardiac index experienced no such correlation. Furthermore, neither stroke volume nor stroke volume index correlated with the corresponding thermodilution-based data. Even though non-invasive estimated continuous cardiac output monitoring consistently underestimated the corresponding thermodilution parameters, no trend analysis was achievable. Summarizing, we cannot suggest the use of non-invasive estimated continuous cardiac output monitoring as an alternative to transpulmonary thermodilution for cardiac output monitoring in pregnant patients undergoing minimally-invasive foetoscopic surgery for spina bifida.

Harvard Citation style: Schneck, E., Drubel, P., Schuerg, R., Markmann, M., Kohl, T., Henrich, M., et al. (2020) Evaluation of pulse wave transit time analysis for non-invasive cardiac output quantification in pregnant patients, Scientific Reports, 10(1), Article 1857. https://doi.org/10.1038/s41598-020-58910-x

APA Citation style: Schneck, E., Drubel, P., Schuerg, R., Markmann, M., Kohl, T., Henrich, M., Sander, M., & Koch, C. (2020). Evaluation of pulse wave transit time analysis for non-invasive cardiac output quantification in pregnant patients. Scientific Reports. 10(1), Article 1857. https://doi.org/10.1038/s41598-020-58910-x