Journal article

Publication year: 2020

Pages: 357-363

Journal: American Journal of Neuroradiology

Volume number: 41

Issue number: 2

ISSN: 0195-6108

eISSN: 1936-959X

Open access status: Hybrid

DOI Link: https://doi.org/10.3174/ajnr.A6372

Publisher: American Society of Neuroradiology

Abstract: 

BACKGROUND AND PURPOSE:

The impact of various radiologic and clinical features on the long-term outcome in spinal dural arteriovenous fistulas is still unclear; thus, they are the purpose of this study.

MATERIALS AND METHODS:

We retrospectively analyzed our medical data base for all patients treated for spinal dural arteriovenous fistula in our institution between 2006 and 2016. Patient age, neurologic status at the time of diagnosis, the duration of symptoms from onset to diagnosis, and follow-up information were evaluated. The extent of medullary T2WI hyperintensity, intramedullary contrast enhancement, and elongation of perimedullary veins on MR imaging at the time of diagnosis were additionally analyzed.

RESULTS:

Data for long-term outcome analysis were available in 40 patients with a mean follow-up of 52?months (median, 50.5?months; range, 3?159?months). The mean age at the time of diagnosis was 69.27 ? 9?years (median, 71 years; range, 53?84 years) with a male predominance (n = 32; 80%). The mean duration of symptoms was 20.2?months (median, 10?months; range, 1?120?months). Shorter duration of symptoms at the time of diagnosis was significantly correlated with better outcome of symptoms (P?

CONCLUSIONS:

Spinal dural arteriovenous fistulas are characterized by interindividually variable clinical presentations, which make a determination of specific predictors for long-term outcome more difficult. Fast and sufficient diagnosis might result in a better outcome after treatment. The diagnosis of spinal dural arteriovenous fistula remains markedly delayed, reflecting an ongoing lack of knowledge and awareness among treating physicians of this rare-but-serious disease.

Harvard Citation style: Jablawi, F., Schubert, G., Dafotakis, M., Pons-Kuehnemann, J., Hans, F. and Mull, M. (2020) Long-Term Outcome of Patients with Spinal Dural Arteriovenous Fistula: The Dilemma of Delayed Diagnosis, American Journal of Neuroradiology, 41(2), pp. 357-363. https://doi.org/10.3174/ajnr.A6372

APA Citation style: Jablawi, F., Schubert, G., Dafotakis, M., Pons-Kuehnemann, J., Hans, F., & Mull, M. (2020). Long-Term Outcome of Patients with Spinal Dural Arteriovenous Fistula: The Dilemma of Delayed Diagnosis. American Journal of Neuroradiology. 41(2), 357-363. https://doi.org/10.3174/ajnr.A6372