Journalartikel

Jahr der Veröffentlichung: 2019

Zeitschrift: BMC Cardiovascular Disorders

Bandnummer: 19

Heftnummer: 1

ISSN: 1471-2261

Open Access Status: Gold

DOI Link: https://doi.org/10.1186/s12872-019-01270-w

Verlag: BioMed Central

Abstract: 
Background Patients after aortic coarctation (CoA) repair show impaired aortic bioelasticity and altered left ventricular (LV) mechanics, predisposing diastolic dysfunction. Our purpose was to assess aortic bioelasticity and LV properties in CoA patients who underwent endovascular stenting or surgery using cardiovascular magnetic resonance (CMR) imaging. Methods Fifty CoA patients (20.5 +/- 9.5 years) were examined by 3-Tesla CMR. Eighteen patients had previous stent implantation and 32 had surgical repair. We performed volumetric analysis of both ventricles (LV, RV) and left atrium (LA) to measure biventricular volumes, ejection fractions, left atrial (LA) volumes, and functional parameters (LAEF(Passive), LAEF(Contractile), LAEF(Reservoir)). Aortic distensibility and pulse wave velocity (PWV) were assessed. Native T1 mapping was applied to examine LV tissue properties. In twelve patients post-contrast T1 mapping was performed. Results LV, RV and LA parameters did not differ between the surgical and stent group. There was also no significant difference for aortic distensibility, PWV and T1 relaxation times. Aortic root distensibility correlated negatively with age, BMI, BSA and weight (p < 0.001). Native T1 values correlated negatively with age, weight, BSA and BMI (p < 0.001). Lower post-contrast T1 values were associated with lower aortic arch distensibility and higher aortic arch PWV (p < 0.001). Conclusions CoA patients after surgery or stent implantation did not show significant difference of aortic elasticity. Thus, presumably other factors like intrinsic aortic abnormalities might have a greater impact on aortic elasticity than the approach of repair. Interestingly, our data suggest that native T1 values are influenced by demographic characteristics.

Harvard-Zitierstil: Pieper, T., Latus, H., Schranz, D., Kreuder, J., Reich, B., Gummel, K., et al. (2019) Aortic elasticity after aortic coarctation relief: comparison of surgical and interventional therapy by cardiovascular magnetic resonance imaging, BMC Cardiovascular Disorders, 19(1), Article 286. https://doi.org/10.1186/s12872-019-01270-w

APA-Zitierstil: Pieper, T., Latus, H., Schranz, D., Kreuder, J., Reich, B., Gummel, K., Hudel, H., & Voges, I. (2019). Aortic elasticity after aortic coarctation relief: comparison of surgical and interventional therapy by cardiovascular magnetic resonance imaging. BMC Cardiovascular Disorders. 19(1), Article 286. https://doi.org/10.1186/s12872-019-01270-w