Journal article

Acute response to rapid iloprost inhalation using the Breelib™ nebulizer in pulmonary arterial hypertension: the Breelib™ acute study


Authors listRichter, Manuel J.; Wan, Jun; Ghofrani, Hossein A.; Seeger, Werner; Gall, Henning; Rieth, Andreas; Tello, Khodr

Publication year2019

JournalPulmonary Circulation

Volume number9

Issue number3

ISSN2045-8932

eISSN2045-8940

Open access statusGold

DOI Linkhttps://doi.org/10.1177/2045894019875342

PublisherWiley


Abstract
The Breelib (TM) nebulizer was designed to reduce iloprost inhalation times for patients with pulmonary arterial hypertension (PAH). In 30 patients with PAH, rapid inhalation of iloprost 2.5 mu g using Breelib (TM) caused significant improvements in invasively measured afterload and cardiac index but not echocardiographic right ventricular strain during 30 min post-inhalation.



Citation Styles

Harvard Citation styleRichter, M., Wan, J., Ghofrani, H., Seeger, W., Gall, H., Rieth, A., et al. (2019) Acute response to rapid iloprost inhalation using the Breelib™ nebulizer in pulmonary arterial hypertension: the Breelib™ acute study, Pulmonary Circulation, 9(3), Article 2045894019875342. https://doi.org/10.1177/2045894019875342

APA Citation styleRichter, M., Wan, J., Ghofrani, H., Seeger, W., Gall, H., Rieth, A., & Tello, K. (2019). Acute response to rapid iloprost inhalation using the Breelib™ nebulizer in pulmonary arterial hypertension: the Breelib™ acute study. Pulmonary Circulation. 9(3), Article 2045894019875342. https://doi.org/10.1177/2045894019875342



Keywords


AEROSOL DELIVERYaerosol drug therapyhemodynamicsINHALED ILOPROSTprostanoidPulmonary hypertensionright ventricular function

Last updated on 2025-10-06 at 11:04