Journalartikel
Autorenliste: Riechmann, Janna; Willems, Laurent M.; Boor, Rainer; Kieslich, Matthias; Knake, Susanne; Langner, Cornelia; Neubauer, Bernd A.; Oberman, Bettina; Philippi, Heike; Reese, Jens P.; Rochel, Michael; Schubert-Bast, Susanne; Seeger, Juergen; Seipelt, Peter; Stephani, Ulrich; Rosenow, Felix; Hamer, Hajo M.; Strzelczyk, Adam
Jahr der Veröffentlichung: 2019
Seiten: 92-98
Zeitschrift: Seizure - European Journal of Epilepsy
Bandnummer: 69
ISSN: 1059-1311
eISSN: 1532-2688
Open Access Status: Bronze
DOI Link: https://doi.org/10.1016/j.seizure.2019.03.016
Verlag: Elsevier
Purpose: To identify factors correlating with poorer quality of life (QoL) in children and adolescents with epilepsy and regarding QoL and depression of their caregivers in Germany. Method: A cross-sectional multicenter study on QoL and depression was performed in two representative German states (Hessen and Schleswig-Holstein). Variance analysis, linear regression, and bivariate correlation were used to identify correlating factors for poorer QoL and symptoms of depression. Results: Data from 489 children and adolescents (mean age 10.4 +/- 4.2 years, range 0.5-17.8; 54.0% male) and their caregivers were collected. We identified missing seizure freedom (p = 0.046), concomitant diseases (p = 0.007), hospitalization (p = 0.049), recent status epilepticus (p = 0.035), living in a nursing home or with foster parents (p = 0.049), and relevant degree of disability (p = 0.007) to correlate with poorer QoL in children and adolescents with epilepsy. Poorer QoL of caregivers was associated with longer disease duration (p = 0.004), non-idiopathic (mainly structural-metabolic) epilepsy (p = 0.003), ongoing seizures (p = 0.003), concomitant diseases (p = 0.003), relevant disability (p = 0.003), or status epilepticus (p = 0.003) as well as with unemployment of the primary caretaker (p = 0.010). Symptoms of depression of caregivers were associated with non-idiopathic epilepsy (p = 0.003), concomitant diseases (p = 0.003), missing seizure freedom (p = 0.007), status epilepticus (p = 0.004), or a relevant disability (p = 0.004) of their ward. A poorer QoL value of the children and adolescents correlated with a poorer QoL value of the caregivers (p < 0.001). Conclusions: Epilepsy shows a considerable impact on QoL and symptoms of depression. Early and effective therapy should focus on reduction of seizure frequency and the probability for developing status epilepticus. Furthermore, comprehensive care should pay attention at comorbidities, consequences of disability and dependency on others.
Abstract:
Zitierstile
Harvard-Zitierstil: Riechmann, J., Willems, L., Boor, R., Kieslich, M., Knake, S., Langner, C., et al. (2019) Quality of life and correlating factors in children, adolescents with epilepsy, and their caregivers: A cross-sectional multicenter study from Germany, Seizure - European Journal of Epilepsy, 69, pp. 92-98. https://doi.org/10.1016/j.seizure.2019.03.016
APA-Zitierstil: Riechmann, J., Willems, L., Boor, R., Kieslich, M., Knake, S., Langner, C., Neubauer, B., Oberman, B., Philippi, H., Reese, J., Rochel, M., Schubert-Bast, S., Seeger, J., Seipelt, P., Stephani, U., Rosenow, F., Hamer, H., & Strzelczyk, A. (2019). Quality of life and correlating factors in children, adolescents with epilepsy, and their caregivers: A cross-sectional multicenter study from Germany. Seizure - European Journal of Epilepsy. 69, 92-98. https://doi.org/10.1016/j.seizure.2019.03.016
Schlagwörter
Anticonvulsants; antiepileptic drug; BECK DEPRESSION; BURDEN; HEALTH-STATUS; ILAE COMMISSION; POSITION PAPER; seizure; STATUS EPILEPTICUS
