Journalartikel

Jahr der Veröffentlichung: 2019

Seiten: 1159-1172

Zeitschrift: European Journal of Nutrition

Bandnummer: 58

Heftnummer: 3

ISSN: 1436-6207

eISSN: 1436-6215

DOI Link: https://doi.org/10.1007/s00394-018-1631-3

Verlag: Springer

Abstract: 
PurposeFlavonoid consumption during adolescence could contribute to preventing adult onset of type 2 diabetes mellitus. We investigated the prospective association between habitual intake of flavonoids from fruit and vegetables (FlavFV) during adolescence and risk markers of type 2 diabetes in early adulthood.MethodsThis analysis included participants of the DONALD Study, who had provided a fasting blood sample in adulthood (18-39years), data on FlavFV-intake during adolescence (females: 9-15years, males: 10-16years) and relevant covariates. Habitual FlavFV-intake was either estimated using repeated 3-day weighed dietary records (n=268), or the validated biomarker hippuric acid (uHA)-excretion in repeated 24-h urine samples (n=241). Multivariable linear regressions were performed to analyse the prospective associations of FlavFV or uHA with homeostasis model assessment insulin sensitivity (HOMA2-%S), hepatic steatosis index (HSI), fatty liver index (FLI) and a pro-inflammatory score.ResultsHigher FlavFV-intake was independently related to higher HOMA2-%S among females (P-trend=0.03), but not among males. Both FlavFV-intake and uHA-excretion were inversely associated with HSI (P-trend<0.0001 and P-trend=0.02, respectively) and the pro-inflammatory score (P-trend=0.02 and P-trend=0.008, respectively), but not with FLI.ConclusionsOur data indicate that flavonoid consumption from fruit and vegetables during adolescence is associated with a favourable risk factor profile for type 2 diabetes in early adulthood.

Harvard-Zitierstil: Penczynski, K., Herder, C., Krupp, D., Rienks, J., Egert, S., Wudy, S., et al. (2019) Flavonoid intake from fruit and vegetables during adolescence is prospectively associated with a favourable risk factor profile for type 2 diabetes in early adulthood, European Journal of Nutrition, 58(3), pp. 1159-1172. https://doi.org/10.1007/s00394-018-1631-3

APA-Zitierstil: Penczynski, K., Herder, C., Krupp, D., Rienks, J., Egert, S., Wudy, S., Roden, M., Remer, T., & Buyken, A. (2019). Flavonoid intake from fruit and vegetables during adolescence is prospectively associated with a favourable risk factor profile for type 2 diabetes in early adulthood. European Journal of Nutrition. 58(3), 1159-1172. https://doi.org/10.1007/s00394-018-1631-3