Journalartikel
Autorenliste: Hrdina, Radim
Jahr der Veröffentlichung: 2019
Seiten: 629-642
Zeitschrift: Synthesis: Journal of Synthetic Organic Chemistry
Bandnummer: 51
Heftnummer: 3
ISSN: 0039-7881
eISSN: 1437-210X
DOI Link: https://doi.org/10.1055/s-0037-1610321
Verlag: Thieme Publishing / Georg Thieme Verlag
This review summarizes the synthetic approaches towards 1,2-substitution pattern on the adamantane framework. Selected are the works containing the directed C-H functionalization step. 1 Introduction 2 Access to 1,2-Disubstituted Derivatives via C-H Insertion Reactions of Electrophilic Organic Species 3 Access to 1,2-Disubstituted Derivatives through Hydrogen Radical Abstraction Reactions 4 Access to 1,2-Disubstituted Derivatives Exploiting Metal-Catalyzed (Promoted) C-H Activations 5 Access to 1,2-Disubstituted Derivatives via Hydride Shift 6 Conclusion 7 Acronyms
Abstract:
Zitierstile
Harvard-Zitierstil: Hrdina, R. (2019) Directed C-H Functionalization of the Adamantane Framework, Synthesis: Journal of Synthetic Organic Chemistry, 51(3), Article ss-2018-z0618-sr. pp. 629-642. https://doi.org/10.1055/s-0037-1610321
APA-Zitierstil: Hrdina, R. (2019). Directed C-H Functionalization of the Adamantane Framework. Synthesis: Journal of Synthetic Organic Chemistry. 51(3), Article ss-2018-z0618-sr, 629-642. https://doi.org/10.1055/s-0037-1610321
Schlagwörter
4,4-DISUBSTITUTED CYCLOHEXANONE ENAMINES; C-H functionalization; C(SP(3))-H BONDS; DELTA-CARBON ATOM; FACILE SYNTHETIC ROUTES; FREE-RADICAL ALKYLATION; hydride shift; hydrogen abstraction reactions; insertion reactions; SATURATED ALCOHOLS; SELECTIVE FUNCTIONALIZATION; SUBSTITUTED ADAMANTANE-2,4-DIONES; TRANSANNULAR CYCLIZATION; TRANSITION-STATE GEOMETRY
