Journal article

Publication year: 2018

Pages: 221-230

Journal: Ophthalmic Research: Journal for Translational and Clinical Research

Volume number: 60

Issue number: 4

ISSN: 0030-3747

eISSN: 1423-0259

DOI Link: https://doi.org/10.1159/000480296

Publisher: Karger Publishers

Abstract: 
Purpose: To correlate visual field assessment with saccadic vector optokinetic perimetry (SVOP) in children with ganglion cell loss due to anterior pathway pathologies resulting in hemianopic visual field defects measured with optical coherence tomography (OCT). Methods: 5 young (aged 3-6 years) and 5 adult patients with hemianopia, 10 healthy preschoolers (mean age 4.4 years), and 10 healthy adults (mean age 25.3 years) were tested with SVOP and OCT (focusing on the ganglion cell layer, GCL+). In adults, visual field testing was also performed with static and fundus-controlled perimetry. Results: OCT allowed precise structure analysis and showed a vertical border with GCL+ loss on the hemianopic side in children and adults compared to controls. SVOP showed visual field defects on the hemianopic side in peripheral regions and inadequate results at the parafoveal positions in both groups. In contrast, static and fundus-controlled perimetry showed a clear border in foveal and parafoveal regions. Conclusions: All children underwent SVOP with minimal restrictions, allowing functional evaluation of peripheral visual field positions. Parafoveal positions showed multiple false-positive results. The function-structure relationship is measurable even in young children by using the GCL+ analysis. This combination of novel child-friendly techniques allows collecting objectively measured values and simplifies diagnosis and follow-up in treatment.

Harvard Citation style: Bowl, W., Knobloch, R., Schweinfurth, S., Holve, K., Stieger, K. and Lorenz, B. (2018) Structure-Function Correlation in Hemianopic Vision Loss in Children Aged 3-6 Years Using OCT and SVOP, and Comparison with Adult Eyes, Ophthalmic Research, 60(4), pp. 221-230. https://doi.org/10.1159/000480296

APA Citation style: Bowl, W., Knobloch, R., Schweinfurth, S., Holve, K., Stieger, K., & Lorenz, B. (2018). Structure-Function Correlation in Hemianopic Vision Loss in Children Aged 3-6 Years Using OCT and SVOP, and Comparison with Adult Eyes. Ophthalmic Research. 60(4), 221-230. https://doi.org/10.1159/000480296