Journalartikel
Autorenliste: Tacke, Moritz; Rupp, Nina; Gerstl, Lucia; Heinen, Florian; Vill, Katharina; Bonfert, Michaela; Neubauer, Bernd Axel; Bast, Thomas; Borggraefe, Ingo
Jahr der Veröffentlichung: 2018
Seiten: 475-481
Zeitschrift: Acta Neurologica Scandinavica
Bandnummer: 138
Heftnummer: 6
ISSN: 0001-6314
eISSN: 1600-0404
DOI Link: https://doi.org/10.1111/ane.13015
Verlag: Wiley
Objectives Neuropsychological sequelae are a feature of benign epilepsy with centrotemporal spikes (BECTS) in children. A correlation between the frequency of interictal EEG discharges and the cognitive as well as behavioral profile of the patients has been suspected but not proven. Materials and methods Children with BECTS that had not yet been treated were included into a randomized controlled trial. In the initial visit, EEGs were recorded. The frequency of interictal discharges was quantified. Correlations between the discharge frequency and the performance in a neuropsychological test battery were examined. Results The cognitive test results were within or slightly above normal range (Culture-free intelligence test: 99.4%-confidence interval [CI]: [50.3, 59.9], test standardized to a population mean of 50). Parent-reported behavioral abnormalities were statistically significantly increased (CBCL total score CI: [51.9, 61.9], population mean as above). Correlations between the frequency of interictal epileptic discharges and the test results could not be identified (lowest encountered P-value: 0.034, not significant after correction for multiple testing). Conclusion The data do not support the hypothesis that the frequency of the interictal EEG discharges influences the neurocognitive performance or behavioral parameters of children with BECTS.
Abstract:
Zitierstile
Harvard-Zitierstil: Tacke, M., Rupp, N., Gerstl, L., Heinen, F., Vill, K., Bonfert, M., et al. (2018) Benign epilepsy with centrotemporal spikes: Correlating spike frequency and neuropsychology, Acta Neurologica Scandinavica, 138(6), pp. 475-481. https://doi.org/10.1111/ane.13015
APA-Zitierstil: Tacke, M., Rupp, N., Gerstl, L., Heinen, F., Vill, K., Bonfert, M., Neubauer, B., Bast, T., & Borggraefe, I. (2018). Benign epilepsy with centrotemporal spikes: Correlating spike frequency and neuropsychology. Acta Neurologica Scandinavica. 138(6), 475-481. https://doi.org/10.1111/ane.13015
Schlagwörter
BECTS; CHILDHOOD EPILEPSY; idiopathic epilepsy; pediatric epilepsy; ROLANDIC EPILEPSY; SULTHIAME; WAVES
