Journalartikel

Jahr der Veröffentlichung: 2018

Seiten: 1551-1557

Zeitschrift: International Journal of Colorectal Disease

Bandnummer: 33

Heftnummer: 11

ISSN: 0179-1958

eISSN: 1432-1262

DOI Link: https://doi.org/10.1007/s00384-018-3142-3

Verlag: Springer

Abstract: 
PurposePostoperative gut dysmotility is a physiologic and frequent temporary reaction after major abdominal surgery. If paralysis merges into a prolonged ileus state, it causes significant morbidity and subsequently worse outcome and discomfort for the patients. Pathophysiology of pathologic prolonged postoperative paralytic ileus remains multifactorial.MethodsWe present a retrospective single-center analysis of patients, who underwent a primary open oncologic anterior rectal resection with primary anastomosis with or without defunctioning loop ileostomy during a 43-month period of observation. Primary endpoint was the rate of prolonged postoperative paralytic ileus, defined by the intravenous administration of neostigmine. Confounders for regression analysis were assessed by univariate analysis and correlations between confounders were examined. Odds ratio for prolonged postoperative paralytic ileus in patients with defunctioning loop ileostomy was estimated by a logistic regression model.ResultsOf 101 patients (62 male), 62 (61.39%) received defunctioning loop ileostomy. In univariate analysis, male gender and patients with ileostomy showed more frequently prolonged paralysis by tendency (both p=0.07). Logistic regression analysis proves the influence of a defunctioning ileostomy on the development of prolonged postoperative paralytic ileus after oncologic rectal resection (p=0.047). Odds ratio for prolonged postoperative paralytic ileus in patients with ileostomy was 4.96 [95% CI 1.02-24.03].ConclusionsAlthough the construction of defunctioning loop ileostomies during rectal resection is a safe, uncomplicated surgical procedure, they can cause significant postoperative morbidity for the patients. High fluid and electrolyte loss are well-known complications, but herewith we raise the evidence for prolonged gut paralysis in patients with defunctioning loop ileostomy.

Harvard-Zitierstil: Reichert, M., Weber, C., Pons-Kuehnemann, J., Hecker, M., Padberg, W. and Hecker, A. (2018) Protective loop ileostomy increases the risk for prolonged postoperative paralytic ileus after open oncologic rectal resection, International Journal of Colorectal Disease, 33(11), pp. 1551-1557. https://doi.org/10.1007/s00384-018-3142-3

APA-Zitierstil: Reichert, M., Weber, C., Pons-Kuehnemann, J., Hecker, M., Padberg, W., & Hecker, A. (2018). Protective loop ileostomy increases the risk for prolonged postoperative paralytic ileus after open oncologic rectal resection. International Journal of Colorectal Disease. 33(11), 1551-1557. https://doi.org/10.1007/s00384-018-3142-3