Journal article

Publication year: 2018

Pages: 2709-2716

Journal: The Journal of Maternal-Fetal & Neonatal Medicine

Volume number: 31

Issue number: 20

ISSN: 1476-7058

eISSN: 1476-4954

DOI Link: https://doi.org/10.1080/14767058.2017.1353970

Publisher: Taylor and Francis Group

Abstract: 
Purpose: We compared outcome of neonates with prenatal and post-natal diagnosis of congenital heart disease presenting in our paediatric heart centre between March 2005 and May 2015 who underwent an emergent intervention within 48h post-partum.Materials and methods: In 52/111 (46.8%) with emergent intervention, congenital heart disease was diagnosed prenatally, in 59/111 (53.2%) with no specialized foetal echocardiography, diagnosis was made post-natally. In 98/111 (88.2%), 30-day outcome was known.Results: Regarding the entire cohort, 30-day survival did not differ significantly in prenatal and post-natal diagnosis group (71.2 vs. 72.9%; p>.1). Infants with prenatal diagnosis were more likely to be born by caesarean section (59.6% vs. 33.9%, p=.01). Those with post-natal diagnosis had a higher need for intubation (32.7% vs. 52.5%; p<.05). Subgroup analysis of HLH/HLHC (hypoplastic left heart/hypoplastic left heart complex) patients revealed higher number of deaths within 30 days of life in the post-natal diagnosis group, although the difference did not reach statistical significance (5/7, 71.4% vs. 5/20, 25.0%; p=.075).Conclusion: For newborns who require emergent neonatal cardiac procedures, our results point towards a lower death rate after prenatal diagnosis of HLH/HLHC.

Harvard Citation style: Wolter, A., Holtmann, H., Kawecki, A., Degenhardt, J., Enzensberger, C., Graupner, O., et al. (2018) Perinatal outcomes of congenital heart disease after emergent neonatal cardiac procedures, The Journal of Maternal-Fetal & Neonatal Medicine, 31(20), pp. 2709-2716. https://doi.org/10.1080/14767058.2017.1353970

APA Citation style: Wolter, A., Holtmann, H., Kawecki, A., Degenhardt, J., Enzensberger, C., Graupner, O., Akintuerk, H., Yerebakan, C., Khalil, M., Schranz, D., & Axt-Fliedner, R. (2018). Perinatal outcomes of congenital heart disease after emergent neonatal cardiac procedures. The Journal of Maternal-Fetal & Neonatal Medicine. 31(20), 2709-2716. https://doi.org/10.1080/14767058.2017.1353970