Journal article
Authors list: Latus, Heiner; Nassar, Mohamed S.; Wong, James; Hachmann, Pauline; Bellsham-Revell, Hannah; Hussain, Tarique; Apitz, Christian; Salih, Caner; Austin, Conal; Anderson, David; Yerebakan, Can; Akintuerk, Hakan; Bauer, Juergen; Razavi, Reza; Schranz, Dietmar; Greil, Gerald
Publication year: 2018
Pages: 244-252
Journal: Heart
Volume number: 104
Issue number: 3
ISSN: 1355-6037
eISSN: 1468-201X
Open access status: Green
DOI Link: https://doi.org/10.1136/heartjnl-2017-311532
Publisher: BMJ Publishing Group
Objective Norwood and hybrid procedure are two options available for initial palliation of patients with hypoplastic left heart syndrome (HLHS). Our study aimed to assess potential differences in right ventricular (RV) function and pulmonary artery dimensions using cardiac magnetic resonance (CMR) in survivors with HLHS. Methods 42 Norwood (mean age 2.4 +/- 0.8) and 44 hybrid (mean age 2.0 +/- 1.0 years) patients were evaluated by CMR after stage II palliation prior to planned Fontan completion. Initial stage I Norwood procedure was performed using a modified Blalock-Taussig shunt, while the hybrid procedure consisted of bilateral pulmonary artery banding and arterial duct stenting. Need for reinterventions and subsequent outcomes were also assessed. Results Norwood patients had larger RV end-diastolic dimensions (91 +/- 23 vs 80 +/- 31 mL/m(2), p=0.004) and lower heart rate (90 +/- 15 vs 102 +/- 13, p<0.001) than hybrid patients. Both Norwood and hybrid patients showed preserved global RV pump function (59 +/- 9 vs 59%+/- 10%, p=0.91), while RV strain, strain rate and intraventricular synchrony were superior in the Norwood group. Pulmonary artery size was reduced (lower lobe index 135 +/- 74 vs 161 +/- 62 mm(2)/m(2), p=0.02), and reintervention rate was significantly higher in the hybrid group whereas subsequent outcome did not differ significantly (p=0.24). Conclusions Norwood and hybrid strategy were associated with equivalent and preserved global RV pump function while development of the pulmonary arteries and reintervention rate were superior using the Norwood approach. Impaired RV myocardial deformation as a potential marker of early RV dysfunction in the hybrid group may have a negative long-term impact in this population.
Abstract:
Citation Styles
Harvard Citation style: Latus, H., Nassar, M., Wong, J., Hachmann, P., Bellsham-Revell, H., Hussain, T., et al. (2018) Ventricular function and vascular dimensions after Norwood and hybrid palliation of hypoplastic left heart syndrome, Heart, 104(3), pp. 244-252. https://doi.org/10.1136/heartjnl-2017-311532
APA Citation style: Latus, H., Nassar, M., Wong, J., Hachmann, P., Bellsham-Revell, H., Hussain, T., Apitz, C., Salih, C., Austin, C., Anderson, D., Yerebakan, C., Akintuerk, H., Bauer, J., Razavi, R., Schranz, D., & Greil, G. (2018). Ventricular function and vascular dimensions after Norwood and hybrid palliation of hypoplastic left heart syndrome. Heart. 104(3), 244-252. https://doi.org/10.1136/heartjnl-2017-311532
Keywords
3 TESLA; CARDIAC SIZE; GRADIENT-ECHO; INTERVENTIONS; OPERATION; STATE FREE PRECESSION; SURGICAL PALLIATION; VOLUMES