Journal article

Publication year: 2017

Pages: 881-888

Journal: American Journal of Physical Medicine & Rehabilitation

Volume number: 96

Issue number: 12

ISSN: 0894-9115

eISSN: 1537-7385

Open access status: Green

DOI Link: https://doi.org/10.1097/PHM.0000000000000781

Publisher: Lippincott, Williams & Wilkins

Abstract: 

Objective The aim of the study was to report physician experience-based real-world treatment patterns with botulinum toxin type A in patients with stroke and traumatic brain injury.

Design A prospective, multicenter, international observational registry design was used.

Results Six hundred twenty-seven participants with stroke and 132 participants with traumatic brain injury were assessed and treated by 17 more experienced physicians and 12 less experienced physicians. Due to the limited usage of abobotulinumtoxinA Dysport and incobotulinumtoxinA Xeomin, data were reported on onabotulinumtoxinA BOTOX only. Based on physician experience, onabotulinumtoxinA doses were statistically different with larger mean doses injected by more experienced physicians in the upper limb (59.9 [39.0], P = 0.001) and in the lower limb (101.8 [69.2], P < 0.001). Treated deformities significantly differed for both upper limb and lower limb (P < 0.001). More experienced physicians showed a larger mean change in Ashworth Scale scores from baseline for the equinovarus/equinus foot and stiff knee (P = 0.001 and 0.03). Less experienced physicians showed a larger mean change in Ashworth Scale scores from baseline for the adducted thigh (P = 0.05). Less experienced physicians had statistically significant larger change in hand pain scores for clenched fist deformity treatment at follow-up compared with more experienced physicians (P = 0.01). Physician experience demonstrated a significant difference on patients reported satisfaction toward their secondary goal with higher scores for more experienced physician (P = 0.04).

Conclusions This international registry provides clinical nuances of treatment based on physician clinical experience in a robust sample size.

Harvard Citation style: Esquenazi, A., Lee, S., Mayer, N., Garreta, R., Patel, A., Elovic, E., et al. (2017) Patient Registry of Spasticity Care World: Data Analysis Based on Physician Experience, American Journal of Physical Medicine & Rehabilitation, 96(12), pp. 881-888. https://doi.org/10.1097/PHM.0000000000000781

APA Citation style: Esquenazi, A., Lee, S., Mayer, N., Garreta, R., Patel, A., Elovic, E., Koelbel, S., Francisco, G., & Reuter, I. (2017). Patient Registry of Spasticity Care World: Data Analysis Based on Physician Experience. American Journal of Physical Medicine & Rehabilitation. 96(12), 881-888. https://doi.org/10.1097/PHM.0000000000000781