Journalartikel
Autorenliste: Weichert, Jan; Hoellen, Friederike; Krapp, Martin; Germer, Ute; Axt-Fliedner, Roland; Kempe, Andrea; Geipel, Annegret; Berg, Christoph; Gembruch, Ulrich
Jahr der Veröffentlichung: 2017
Seiten: 455-463
Zeitschrift: Archives of Gynecology and Obstetrics
Bandnummer: 296
Heftnummer: 3
ISSN: 0932-0067
eISSN: 1432-0711
DOI Link: https://doi.org/10.1007/s00404-017-4424-7
Verlag: Springer
To scrutinize the characteristics of all cases with antenatally established diagnosis of cephalocele in two tertiary referral centers. We retrospectively reviewed 65 cases diagnosed with cephaloceles and tabulated sonographic findings and autopsy recordings as well as medical charts of all survivors in terms of clinical outcome. The case notes of 65 fetuses were available for final analysis. Gestational age (GA) at diagnosis ranged from 10.4 to 38.1 weeks. Of our cohort, 53/65 cases (80%) had occipital protrusions, 10 (15%) were found to have frontal lesions, and another two had parietal cephaloceles. A total of 52 pregnancies were terminated or resulted in intrauterine fetal demise (78%). In 18 cases (11%), the cephalocele was part of underlying syndromic disorders (e.g., Meckel-Gruber syndrome). Thirteen pregnancies were continued until term, out of which all affected individuals were live-born. Neurosurgical intervention was prompted within the first 7 months postnatally. In general, the outcome of fetuses with cephaloceles is rather poor as four out of five pregnancies were terminated. Postnatal outcome of all survivors in our cohort was rather determined by localization of the cele and more important by the presence and severity of concomitant malformations than the extent of the lesion.
Abstract:
Zitierstile
Harvard-Zitierstil: Weichert, J., Hoellen, F., Krapp, M., Germer, U., Axt-Fliedner, R., Kempe, A., et al. (2017) Fetal cephaloceles: prenatal diagnosis and course of pregnancy in 65 consecutive cases, Archives of Gynecology and Obstetrics, 296(3), pp. 455-463. https://doi.org/10.1007/s00404-017-4424-7
APA-Zitierstil: Weichert, J., Hoellen, F., Krapp, M., Germer, U., Axt-Fliedner, R., Kempe, A., Geipel, A., Berg, C., & Gembruch, U. (2017). Fetal cephaloceles: prenatal diagnosis and course of pregnancy in 65 consecutive cases. Archives of Gynecology and Obstetrics. 296(3), 455-463. https://doi.org/10.1007/s00404-017-4424-7
Schlagwörter
Cephalocele; Encephalocele; ENCEPHALOCELE; FETUS; Meningocele; MENINGOCELE; NEURAL-TUBE DEFECTS; prenatal; SCALP CYST; SONOGRAPHIC SPECTRUM; ultrasonography; WEEKS GESTATION
