Journal article

The impact of baroreflex function on endogenous pain control: a microneurography study


Authors list: Lautenschlaeger, Gothje; Habig, Kathrin; Best, Christoph; Kaps, Manfred; Elam, Mikael; Birklein, Frank; Kraemer, Heidrun H.

Publication year: 2015

Pages: 2996-3003

Journal: European Journal of Neuroscience

Volume number: 42

Issue number: 11

ISSN: 0953-816X

eISSN: 1460-9568

DOI Link: https://doi.org/10.1111/ejn.13096

Publisher: Wiley


Abstract: 
The interaction between sympathetic vasoconstrictor activity to muscles [muscle sympathetic nerve activity (MSNA), burst frequency (BF) and burst incidence (BI)] and different stress and somatosensory stimuli is still unclear. Eighteen healthy men (median age 28 years) underwent microneurography recordings from the peroneal nerve. MSNA was recorded during heat pain (HP) and cold pain (CP) alone as well as combined with different stress tasks (mental arithmetic, singing, giving a speech). An additional nine healthy men (median age 26 years) underwent the stimulation protocol with an additional control task (thermal pain combined with listening to music) to evaluate possible attentional confounders. MSNA was significantly increased by CP and HP. CP-evoked responses were smaller. The diastolic blood pressure followed the time course of MSNA while heart rate remained unchanged. The mental stress tasks further increased MSNA and were sufficient to reduce pain while the control task had no effect. MSNA activity correlated negatively with pain intensity and positively with analgesia. High blood pressure values were associated with lower pain intensity. Our study indicates an impact of central sympathetic drive on pain and pain control.



Citation Styles

Harvard Citation style: Lautenschlaeger, G., Habig, K., Best, C., Kaps, M., Elam, M., Birklein, F., et al. (2015) The impact of baroreflex function on endogenous pain control: a microneurography study, European Journal of Neuroscience, 42(11), pp. 2996-3003. https://doi.org/10.1111/ejn.13096

APA Citation style: Lautenschlaeger, G., Habig, K., Best, C., Kaps, M., Elam, M., Birklein, F., & Kraemer, H. (2015). The impact of baroreflex function on endogenous pain control: a microneurography study. European Journal of Neuroscience. 42(11), 2996-3003. https://doi.org/10.1111/ejn.13096



Keywords

BLOOD-PRESSURE; HEART-RATE; MENTAL STRESS; mental stress tasks; MSNA; MUSCLE PAIN; NOXIOUS-STIMULATION; stress-induced analgesia; STRESS-INDUCED ANALGESIA; SYMPATHETIC-NERVE ACTIVITY; thermal pain

Last updated on 2025-21-05 at 18:34