Contribution in an anthology

Appeared in: INTRAVENOUS LIPID EMULSIONS

Editor list: Calder, PC; Waitzberg, DL; Koletzko, B

Publication year: 2015

Pages: 120-126

Volume number: 112

ISSN: 0084-2230

ISBN: 978-3-318-02752-5

eISSN: 1662-3975

eISBN: 978-3-318-02753-2

DOI Link: https://doi.org/10.1159/000365667

Title of series: World Review of Nutrition and Dietetics

Abstract: 
Malnutrition of critically ill patients is a widespread phenomenon in intensive care units (ICUs) worldwide. Lipid emulsions (LEs) are able to provide sufficient caloric support and essential fatty acids to correct the energy deficit and improve outcome. Furthermore, components of LEs might impact cell and organ function in an ICU setting. All currently available LEs for parenteral use are effective in providing energy and possess a good safety profile. Nevertheless, soybean oil-based LEs have been associated with an elevated risk of adverse outcomes, possibly due to their high content of omega-6 fatty acids. More newly developed emulsions partially replace soybean oil with medium-chain triglycerides, fish oil or olive oil in various combinations to reduce its negative effects on immune function and inflammation. The majority of experimental studies and smaller clinical trials provide initial evidence for a beneficial impact of these modern LEs on critically ill patients. However, large, well-designed clinical trials are needed to evaluate which LE offers the greatest advantages concerning clinical outcome. Lipid emulsions (LEs) are a powerful source of energy that can help to adjust the caloric deficit of intensive care unit (ICU) patients. LEs possess various biological activities, but their subsequent impact on critically ill patients awaits further investigations. (C) 2015 S. Karger AG, Basel

Harvard Citation style: Hecker, M. and Mayer, K. (2015) Intravenous Lipids in Adult Intensive Care Unit Patients, in Calder, P., Waitzberg, D. and Koletzko, B. (eds.) INTRAVENOUS LIPID EMULSIONS. KARGER, pp. 120-126. https://doi.org/10.1159/000365667

APA Citation style: Hecker, M., & Mayer, K. (2015). Intravenous Lipids in Adult Intensive Care Unit Patients. In Calder, P., Waitzberg, D., & Koletzko, B. (Eds.), INTRAVENOUS LIPID EMULSIONS (pp. 120-126). KARGER. https://doi.org/10.1159/000365667