Journalartikel

Jahr der Veröffentlichung: 2015

Seiten: 104-118

Zeitschrift: Journal of Biomaterials Applications

Bandnummer: 30

Heftnummer: 1

ISSN: 0885-3282

eISSN: 1530-8022

DOI Link: https://doi.org/10.1177/0885328215572428

Verlag: SAGE Publications

Abstract: 
An important challenge in the field of dental and orthopedic implantology is the preparation of implant coatings with bioactive functions that feature a high mechanical stability and at the same time mimic structural and compositional properties of native bone for a better bone ingrowth. This study investigates the influence of magnesium addition to zirconia-calcium phosphate coatings. The mixed coatings were prepared with varying additions of either magnesium oxide or magnesium fluoride to yttria-stabilized zirconia and hydroxyapatite. The coatings were deposited on zirconia discs and screw implants by wet powder spraying. Microstructure studies confirm a porous coating with similar roughness and firm adhesion not hampered by the coating composition. The coating morphology, mechanical flexural strength and calcium dissolution showed a magnesium content-dependent effect. Moreover, the invitro results obtained with human osteoblasts reveal an improved biological performance caused by the presence of Mg2+ ions. The magnesium-containing coatings exhibited better cell proliferation and differentiation in comparison to pure zirconia-calcium phosphate coatings. In conclusion, these results demonstrate that magnesium addition increases the bioactivity potential of zirconia-calcium phosphate coatings and is thus a highly suitable candidate for bone implant coatings.

Harvard-Zitierstil: Pardun, K., Treccani, L., Volkmann, E., Streckbein, P., Heiss, C., Gerlach, J., et al. (2015) Magnesium-containing mixed coatings on zirconia for dental implants: mechanical characterization and invitro behavior, Journal of Biomaterials Applications, 30(1), pp. 104-118. https://doi.org/10.1177/0885328215572428

APA-Zitierstil: Pardun, K., Treccani, L., Volkmann, E., Streckbein, P., Heiss, C., Gerlach, J., Maendl, S., & Rezwan, K. (2015). Magnesium-containing mixed coatings on zirconia for dental implants: mechanical characterization and invitro behavior. Journal of Biomaterials Applications. 30(1), 104-118. https://doi.org/10.1177/0885328215572428