Journal article
Authors list: Eckhard, M.; Kroell, K. P.; Karrasch, T.; Roller, F.; Feek, U.; Lange, U.; Noethe, M.; Seeger, W.; Ghofrani, S.; Schaeffler, A.
Publication year: 2015
Pages: 696-69+
Journal: Der Internist
Volume number: 56
Issue number: 6
ISSN: 0020-9554
eISSN: 1432-1289
DOI Link: https://doi.org/10.1007/s00108-015-3710-3
Publisher: Springer
Abstract:
This article reports a case of febrile, symmetrical and painful soft tissue swelling on both thighs in a 54-year-old otherwise healthy male patient. Histologically, necrotizing panniculitis of subcutaneous adipose tissue was described as a marker manifestation of a previously unknown alpha-1-antitrypsin (A1AT) deficiency with pulmonary emphysema and low plasma A1AT levels. The PiZZ homozygous form of A1AT could be diagnosed by gene sequencing. Complete remission of panniculitis could be achieved by A1AT replacement therapy.
Citation Styles
Harvard Citation style: Eckhard, M., Kroell, K., Karrasch, T., Roller, F., Feek, U., Lange, U., et al. (2015) Panniculitis of the thigh and lung emphysema in a 54-year-old patient, Der Internist, 56(6), pp. 696-69+. https://doi.org/10.1007/s00108-015-3710-3
APA Citation style: Eckhard, M., Kroell, K., Karrasch, T., Roller, F., Feek, U., Lange, U., Noethe, M., Seeger, W., Ghofrani, S., & Schaeffler, A. (2015). Panniculitis of the thigh and lung emphysema in a 54-year-old patient. Der Internist. 56(6), 696-69+. https://doi.org/10.1007/s00108-015-3710-3
Keywords
ALPHA-1-ANTITRYPSIN; alpha 1 antitrypsin deficiency; PROTEASE INHIBITORS; Soft tissue edema
