Journalartikel

Comorbidities Frequency in Takotsubo Syndrome: An International Collaborative Systematic Review Including 1109 Patients


AutorenlistePelliccia, Francesco; Parodi, Guido; Greco, Cesare; Antoniucci, David; Brenner, Roman; Bossone, Eduardo; Cacciotti, Luca; Capucci, Alessandro; Citro, Rodolfo; Delmas, Clement; Guerra, Federico; Ionescu, Costin N.; Lairez, Olivier; Larrauri-Reyes, Maiteder; Lee, Pil Hyung; Mansencal, Nicolas; Marazzi, Giuseppe; Mihos, Christos G.; Morel, Olivier; Nef, Holger M.; Nunez Gil, Ivan J.; Passaseo, Ilaria; Pineda, Andres M.; Rosano, Giuseppe; Santana, Orlando; Schneck, Franziska; Song, Bong Gun; Song, Jae-Kwan; Teh, Andrew W.; Ungprasert, Patompong; Valbusa, Alberto; Wahl, Andreas; Yoshida, Tetsuro; Gaudio, Carlo; Kaski, Juan Carlos

Jahr der Veröffentlichung2015

ZeitschriftThe American Journal of Medicine

Bandnummer128

Heftnummer6

ISSN0002-9343

eISSN1555-7162

DOI Linkhttps://doi.org/10.1016/j.amjmed.2015.01.016

VerlagElsevier


Abstract

BACKGROUND: To identify predisposing factors that can result in the onset of takotsubo syndrome, we performed an international, collaborative systematic review focusing on clinical characteristics and comorbidities of patients with takotsubo syndrome.

METHODS: We searched and reviewed cited references up to August 2013 to identify relevant studies. Corresponding authors of selected studies were contacted and asked to provide additional quantitative details. Data from each study were extracted by 2 independent reviewers. The cumulative prevalence of presenting features and comorbidities was assessed. Nineteen studies whose authors sent the requested information were included in the systematic review, with a total of 1109 patients (951 women; mean age, 59-76 years). Evaluation of risk factors showed that obesity was present in 17% of patients (range, 2%-48%), hypertension in 54% (range, 27%-83%), dyslipidemia in 32% (range, 7%-59%), diabetes in 17% (range, 4%-34%), and smoking in 22% (range, 6%-49%). Emotional stressors preceded takotsubo syndrome in 39% of patients and physical stressors in 35%. The most common comorbidities were psychological disorders (24%; range, 0-49%), pulmonary diseases (15%; range, 0-22%), and malignancies (10%; range, 4%-29%). Other common associated disorders were neurologic diseases (7%; range, 0-22%), chronic kidney disease (7%; range, 2%-27%), and thyroid diseases (6%; range, 0-37%).

CONCLUSIONS: Patients with takotsubo syndrome have a relevant prevalence of cardiovascular risk factors and associated comorbidities. Such of associations needs to be evaluated in further studies. (C) 2015 Elsevier Inc. All rights reserved.




Zitierstile

Harvard-ZitierstilPelliccia, F., Parodi, G., Greco, C., Antoniucci, D., Brenner, R., Bossone, E., et al. (2015) Comorbidities Frequency in Takotsubo Syndrome: An International Collaborative Systematic Review Including 1109 Patients, The American Journal of Medicine, 128(6), Article 654.e11. https://doi.org/10.1016/j.amjmed.2015.01.016

APA-ZitierstilPelliccia, F., Parodi, G., Greco, C., Antoniucci, D., Brenner, R., Bossone, E., Cacciotti, L., Capucci, A., Citro, R., Delmas, C., Guerra, F., Ionescu, C., Lairez, O., Larrauri-Reyes, M., Lee, P., Mansencal, N., Marazzi, G., Mihos, C., Morel, O., ...Kaski, J. (2015). Comorbidities Frequency in Takotsubo Syndrome: An International Collaborative Systematic Review Including 1109 Patients. The American Journal of Medicine. 128(6), Article 654.e11. https://doi.org/10.1016/j.amjmed.2015.01.016



Schlagwörter


Acute left ventricular dysfunctionApical ballooning syndromeAPICAL BALLOONING SYNDROMECardiomyopathyCLINICAL CHARACTERISTICSSTRESS-INDUCED CARDIOMYOPATHYTakotsubo cardiomyopathyTAKO-TSUBO CARDIOMYOPATHYTakotsubo syndromeTERM-FOLLOW-UP

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