Journal article

Publication year: 2015

Pages: 150-156

Journal: Chemosphere

Volume number: 129

ISSN: 0045-6535

eISSN: 1879-1298

DOI Link: https://doi.org/10.1016/j.chemosphere.2014.06.061

Publisher: Elsevier

Abstract: 
Tissue specific uptake and elimination of perfluoroalkyl acids (PFAAs) were studied in rainbow trout (Oncorhynchus mykiss), Adult trout were exposed to perfluorobutane sulfonic acid (PFBS), perfluorohexane sulfonic acid (PFHxS), perfluorooctane sulfonic acid (PFOS), perfluorooctanoic acid (PFOA) and perfluorononanoic acid (PFNA) via food over a time period of 28 d. In the following 28-d deputation period the fish were fed PFAA-free food. At defined sampling times four animals were removed from the experimental tank, euthanized and dissected. Muscle, liver, kidneys, gills, blood, skin and carcass were examined individually. At the end of the accumulation phase between 0.63% (PFOA) and 15.5% (PFOS) of the absolute, applied quantity of PFAAs was recovered in the whole fish. The main target organ was the liver with recovery rates between 0.11% (PFBS) and 4.01% (PFOS) of the total amount of ingested PFAAs. Perfluoroalkyl sulfonic acids were taken up more readily and had longer estimated elimination half-lives than perfluoroalkyl carboxylic acids of the same chain length. The longest estimated elimination half-lives were found to be for PFOS between 8.4 d in muscle tissue and 20.4 d in the liver and for PFNA between 8.2 d in the blood and 11.6 d in the liver. (C) 2014 Elsevier Ltd. All rights reserved.

Harvard Citation style: Falk, S., Failing, K., Georgii, S., Brunn, H. and Stahl, T. (2015) Tissue specific uptake and elimination of perfluoroalkyl acids (PFAAs) in adult rainbow trout (Oncorhynchus mykiss) after dietary exposure, Chemosphere, 129, pp. 150-156. https://doi.org/10.1016/j.chemosphere.2014.06.061

APA Citation style: Falk, S., Failing, K., Georgii, S., Brunn, H., & Stahl, T. (2015). Tissue specific uptake and elimination of perfluoroalkyl acids (PFAAs) in adult rainbow trout (Oncorhynchus mykiss) after dietary exposure. Chemosphere. 129, 150-156. https://doi.org/10.1016/j.chemosphere.2014.06.061