Journal article

Publication year: 2015

Pages: 1112-1120

Journal: The Journal of Thoracic and Cardiovascular Surgery

Volume number: 149

Issue number: 4

ISSN: 0022-5223

eISSN: 1097-685X

Open access status: Bronze

DOI Link: https://doi.org/10.1016/j.jtcvs.2014.09.028

Publisher: Elsevier

Abstract: 

Objective: This article presents the long-term results of our patients with a diagnosis of hypoplastic left heart syndrome (HLHS), hypoplastic left heart complex (HLHC), and variants who received a biventricular repair following hybrid stage I with ductal stenting and bilateral pulmonary artery banding.

Methods: Between June 1998 and June 2013, a total of 154 patients with hypoplastic left heart structures underwent a hybrid stage I procedure. Forty patients were definitely treated by creating a biventricular circulation. Median age and body weight of patients before hybrid stage I were 8.5 days (2-40) and 3.0 kg (1.6-3.8), respectively. The diagnoses were HLHS with mitral and aortic stenosis (n = 7), HLHC (n = 15), HLHC with interrupted aortic arch (n = 9), critical aortic stenosis with hypoplastic aortic arch (n = 4), imbalanced atrioventricular septal defect with hypoplastic aortic arch (n = 2), double-outlet right ventricle with hypoplastic aortic arch (n = 2), and d-transposition of the great arteries with interrupted aortic arch (n = 1). Median age at the time of biventricular correction was 6.7 months (1.6-13.8). The patients were treated with direct biventricular correction, including repair of intracardiac defects (n = 32), Norwood/Rastelli or Yasui (n = 4), arterial switch (n = 2), Rastelli (n = 1), and Ross-Konno (n = 1) operations with ascending aortic/aortic arch reconstruction.

Results: All patients survived hybrid stage I. Median survival after biventricular correction is 7.9 years (0.9-14.9). Overall mortality was 10% (4 patients) at 4 weeks, 5 weeks, 6 weeks, and 4 months after biventricular correction, respectively. One patient had to be switched to univentricular circulation and another patient underwent orthotopic heart transplantation 3 and 4 months after biventricular correction, respectively.

Conclusions: The Giessen hybrid approach is an alternative to the conventional strategy to treat neonates with HLHS, HLHC, and variants. Biventricular repair after hybrid stage I is feasible and can be performed with satisfactory long-term survival.

Harvard Citation style: Yerebakan, C., Murray, J., Valeske, K., Thul, J., Elmontaser, H., Mueller, M., et al. (2015) Long-term results of biventricular repair after initial Giessen hybrid approach for hypoplastic left heart variants, The Journal of Thoracic and Cardiovascular Surgery, 149(4), pp. 1112-1120. https://doi.org/10.1016/j.jtcvs.2014.09.028

APA Citation style: Yerebakan, C., Murray, J., Valeske, K., Thul, J., Elmontaser, H., Mueller, M., Mann, V., Ostermayer, S., Latus, H., Apitz, C., Schranz, D., & Akintuerk, H. (2015). Long-term results of biventricular repair after initial Giessen hybrid approach for hypoplastic left heart variants. The Journal of Thoracic and Cardiovascular Surgery. 149(4), 1112-1120. https://doi.org/10.1016/j.jtcvs.2014.09.028