Journalartikel

Jahr der Veröffentlichung: 2015

Seiten: 583-597

Zeitschrift: Future Microbiology

Bandnummer: 10

Heftnummer: 4

ISSN: 1746-0913

eISSN: 1746-0921

DOI Link: https://doi.org/10.2217/FMB.15.4

Verlag: Taylor and Francis Group

Abstract: 
Listeria monocytogenes is a facultative intracellular bacterium causing listeriosis, a food-borne infection with a high mortality rate. The mechanisms and the role of cells and tissular components in generating protective adaptive immune responses are well studied, and cell biological studies provide a detailed understanding of the processes targeted by the bacterial products. Much less is known of the cellular responses activated to limit infection in individual cells when confronted with stress or infection. Eukaryotic cellular responses depend on multitiered homeostatic systems that ensure maintenance of proteostatis, organellar integrity, function and turnover, and overall cellular viability ('the cell-autonomous response'). Here, we review the cell-autonomous responses induced during extracellular and intracellular L. monocytogenes growth and discuss their contribution to limiting infection.

Harvard-Zitierstil: Pillich, H., Chakraborty, T. and Abu Mraheil, M. (2015) Cell-autonomous responses in Listeria monocytogenes infection, Future Microbiology, 10(4), pp. 583-597. https://doi.org/10.2217/FMB.15.4

APA-Zitierstil: Pillich, H., Chakraborty, T., & Abu Mraheil, M. (2015). Cell-autonomous responses in Listeria monocytogenes infection. Future Microbiology. 10(4), 583-597. https://doi.org/10.2217/FMB.15.4