Poor sleep quality is associated with exercise limitation in precapillary pulmonary hypertension - Forschungsportal der Justus-Liebig-Universität Gießen:

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Poor sleep quality is associated with exercise limitation in precapillary pulmonary hypertension

Autorenliste: Tiede, Henning; Rorzyczka, Janet; Dumitrascu, Rio; Belly, Michael; Reichenberger, Frank; Ghofrani, Hossein Ardeschir; Seeger, Werner; Heitmann, Joerg; Schulz, Richard

Jahr der Veröffentlichung: 2015

Zeitschrift: BMC Pulmonary Medicine

Bandnummer: 15

ISSN: 1471-2466

Open Access Status: Gold

DOI Link: https://doi.org/10.1186/s12890-015-0005-3

Verlag: BioMed Central

Abstract:

Background: Patients with precapillary pulmonary hypertension (PH) have been reported to suffer from poor sleep quality, however, if this is related to physical exercise performance has not yet been thoroughly investigated.

Methods: Clinically stable out-patients with idiopathic pulmonary arterial hypertension (IPAH, n = 52) and chronic thromboembolic PH (CTEPH, n = 64) in NYHA classes II and III were prospectively enrolled. 54 healthy volunteers matched for anthropometric variables served as a control group. The Pittsburgh Sleep Quality Index (PSQI) was used to rate subjective sleep quality. In the PH patients, six-minute walk tests (6MWT) were performed to assess exercise capacity.

Results: Poor sleep quality (i.e. a PSQI score > 5) occurred more frequently in PH (IPAH: n = 25 [ 48.1%], CTEPH: n = 39 [60.9%], controls: n = 10 [18.5%]; p < 0.01 when compared to controls). In addition, poor vs. good sleepers had significantly higher average NYHA class (IPAH: 2.6 +/- 0.1 vs. 2.3 +/- 0.1, CTEPH: 2.8 +/- 0.1 vs. 2.3 +/- 0.2; p < 0.01) and shorter 6MWT distances (IPAH: 338 +/- 23 vs. 441 +/- 29 m, CTEPH: 355 +/- 15 vs. 413 +/- 26 m; p < 0.05).

Conclusions: Self-reported poor sleep quality is more common in PH than in healthy controls. Furthermore, it is related to reduced physical exercise capacity.

Zitierstile

Harvard-Zitierstil: Tiede, H., Rorzyczka, J., Dumitrascu, R., Belly, M., Reichenberger, F., Ghofrani, H., et al. (2015) Poor sleep quality is associated with exercise limitation in precapillary pulmonary hypertension, BMC Pulmonary Medicine, 15, Article 11. https://doi.org/10.1186/s12890-015-0005-3

APA-Zitierstil: Tiede, H., Rorzyczka, J., Dumitrascu, R., Belly, M., Reichenberger, F., Ghofrani, H., Seeger, W., Heitmann, J., & Schulz, R. (2015). Poor sleep quality is associated with exercise limitation in precapillary pulmonary hypertension. BMC Pulmonary Medicine. 15, Article 11. https://doi.org/10.1186/s12890-015-0005-3

Zitierstile

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