Journal article
Authors list: Reichert, M.; Hecker, M.; Hoerbelt, R.; Lerner, S.; Hoeller, J.; Hecker, C. M.; Padberg, W.; Weigand, M. A.; Hecker, A.
Publication year: 2015
Pages: 47-55
Journal: Der Chirurg
Volume number: 86
Issue number: 1
ISSN: 0009-4722
eISSN: 1433-0385
DOI Link: https://doi.org/10.1007/s00104-014-2887-7
Publisher: Springer
Acute mesenteric ischemia is a severe and challenging disease. Unspecific symptoms in the initial phase make a fast diagnosis difficult although it is of major importance to protect patients from irreversible ischemia, extended bowel resection, sepsis and death in the late phase. In contrast to troponin as an early biomarker for cardiac ischemia, a reliable biomarker for acute intestinal ischemia has not yet been identified in the current literature and clinical practice. This would allow the early identification of these critically ill patients in the initial reversible phase of acute intestinal ischemia. This review highlights the pathophysiology, epidemiology and clinical findings of acute mesenteric ischemia and gives an overview of biomarkers which have been investigated in mesenteric ischemia with a special focus on lactate, which is the only parameter routinely used in the diagnostic setting of acute mesenteric ischemia.
Abstract:
Citation Styles
Harvard Citation style: Reichert, M., Hecker, M., Hoerbelt, R., Lerner, S., Hoeller, J., Hecker, C., et al. (2015) The role of biomarkers in the diagnostics of acute mesenteric ischemia, Der Chirurg, 86(1), pp. 47-55. https://doi.org/10.1007/s00104-014-2887-7
APA Citation style: Reichert, M., Hecker, M., Hoerbelt, R., Lerner, S., Hoeller, J., Hecker, C., Padberg, W., Weigand, M., & Hecker, A. (2015). The role of biomarkers in the diagnostics of acute mesenteric ischemia. Der Chirurg. 86(1), 47-55. https://doi.org/10.1007/s00104-014-2887-7
Keywords
ACUTE INTESTINAL ISCHEMIA; Acute mesenteric ischemia; CARDIOGENIC-SHOCK; EARLY LACTATE CLEARANCE; lactate; LACTIC-ACIDOSIS; ORGAN FAILURE; SEPTIC SHOCK; serum lactate; SEVERE SEPSIS; SYMPTOMS