Journal article

The role of biomarkers in the diagnostics of acute mesenteric ischemia


Authors listReichert, M.; Hecker, M.; Hoerbelt, R.; Lerner, S.; Hoeller, J.; Hecker, C. M.; Padberg, W.; Weigand, M. A.; Hecker, A.

Publication year2015

Pages47-55

JournalDer Chirurg

Volume number86

Issue number1

ISSN0009-4722

eISSN1433-0385

DOI Linkhttps://doi.org/10.1007/s00104-014-2887-7

PublisherSpringer


Abstract

Acute mesenteric ischemia is a severe and challenging disease. Unspecific symptoms in the initial phase make a fast diagnosis difficult although it is of major importance to protect patients from irreversible ischemia, extended bowel resection, sepsis and death in the late phase. In contrast to troponin as an early biomarker for cardiac ischemia, a reliable biomarker for acute intestinal ischemia has not yet been identified in the current literature and clinical practice. This would allow the early identification of these critically ill patients in the initial reversible phase of acute intestinal ischemia.

This review highlights the pathophysiology, epidemiology and clinical findings of acute mesenteric ischemia and gives an overview of biomarkers which have been investigated in mesenteric ischemia with a special focus on lactate, which is the only parameter routinely used in the diagnostic setting of acute mesenteric ischemia.




Citation Styles

Harvard Citation styleReichert, M., Hecker, M., Hoerbelt, R., Lerner, S., Hoeller, J., Hecker, C., et al. (2015) The role of biomarkers in the diagnostics of acute mesenteric ischemia, Der Chirurg, 86(1), pp. 47-55. https://doi.org/10.1007/s00104-014-2887-7

APA Citation styleReichert, M., Hecker, M., Hoerbelt, R., Lerner, S., Hoeller, J., Hecker, C., Padberg, W., Weigand, M., & Hecker, A. (2015). The role of biomarkers in the diagnostics of acute mesenteric ischemia. Der Chirurg. 86(1), 47-55. https://doi.org/10.1007/s00104-014-2887-7



Keywords


ACUTE INTESTINAL ISCHEMIAAcute mesenteric ischemiaCARDIOGENIC-SHOCKEARLY LACTATE CLEARANCElactateLACTIC-ACIDOSISORGAN FAILURESEPTIC SHOCKserum lactateSEVERE SEPSISSYMPTOMS

Last updated on 2025-21-05 at 18:36