Journal article

Publication year: 2014

Pages: S89-S95

Journal: Epileptic Disorders

Volume number: 16

ISSN: 1294-9361

eISSN: 1950-6945

DOI Link: https://doi.org/10.1684/epd.2014.0688

Publisher: Wiley

Abstract: 
Status epilepticus (SE) is a medical emergency with increased risk of morbidity and mortality in all age groups. Recent research has identified a variety of new genes implicated in disorders with severe epilepsies as a prominent feature. Autoimmune mechanisms have also been recently recognised as a cause of epilepsies with SE as a characteristic symptom. Knowledge about the aetiology potentially underlying SE may help to guide diagnostics and eventually influence treatment decisions. This review recapitulates, in brief, the risk of SE in specific clinical settings, provides an overview of paediatric epilepsy syndromes more commonly, or by definition, associated with SE, and summarizes some recent research data on genetic defects and disease mechanisms implicated in the pathogenesis of epilepsies frequently accompanied by SE.

Harvard Citation style: Neubauer, B. and Hahn, A. (2014) Syndromes at risk of status epilepticus in children: genetic and pathophysiological issues, Epileptic Disorders, 16, pp. S89-S95. https://doi.org/10.1684/epd.2014.0688

APA Citation style: Neubauer, B., & Hahn, A. (2014). Syndromes at risk of status epilepticus in children: genetic and pathophysiological issues. Epileptic Disorders. 16, S89-S95. https://doi.org/10.1684/epd.2014.0688