Journalartikel

A single center comparison between three different apheresis systems for autologous and allogeneic stem cell collections


AutorenlisteFlommersfeld, Sabine; Bakchoul, Tamam; Bein, Gregor; Wachtel, Almut; Loechelt, Cordula; Sachs, Ulrich J.

Jahr der Veröffentlichung2013

Seiten428-433

ZeitschriftTransfusion and Apheresis Science

Bandnummer49

Heftnummer3

ISSN1473-0502

DOI Linkhttps://doi.org/10.1016/j.transci.2013.06.002

VerlagElsevier


Abstract
Three different apheresis systems were used in our center for the collection of peripheral blood progenitor cells (PBPCs): COM.TEC (Fresenius Healthcare), CUBE Spectra, and Spectra Optia (both from Caridian BCT). We compared 131 autologous and 56 allogeneic apheresis procedures to elucidate feasibility and effectiveness of the different systems. Collection efficiacy varied significantly with lowest results obtained with CUBE Spectra. COM.TEC and Spectra Optia produced lower WBC contamination than CUBE Spectra, but at the expense of higher product volume and longer apheresis time. High collection efficacy and a low product volume may be favorable characteristics of the Spectra Optia. (C) 2013 Elsevier Ltd. All rights reserved.



Zitierstile

Harvard-ZitierstilFlommersfeld, S., Bakchoul, T., Bein, G., Wachtel, A., Loechelt, C. and Sachs, U. (2013) A single center comparison between three different apheresis systems for autologous and allogeneic stem cell collections, Transfusion and Apheresis Science, 49(3), pp. 428-433. https://doi.org/10.1016/j.transci.2013.06.002

APA-ZitierstilFlommersfeld, S., Bakchoul, T., Bein, G., Wachtel, A., Loechelt, C., & Sachs, U. (2013). A single center comparison between three different apheresis systems for autologous and allogeneic stem cell collections. Transfusion and Apheresis Science. 49(3), 428-433. https://doi.org/10.1016/j.transci.2013.06.002



Schlagwörter


Apheresis proceduresBLOOD PROGENITOR CELLSBONE-MARROWCollection efficacyCOUNTSPROTOCOLSSEPARATORSStem cell collectionTRANSPLANTATION


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