Journalartikel
Autorenliste: Herold, Susanne; Gabrielli, Nieves M.; Vadasz, Istvan
Jahr der Veröffentlichung: 2013
Seiten: L665-L681
Zeitschrift: American Journal of Physiology - Lung Cellular and Molecular Physiology
Bandnummer: 305
Heftnummer: 10
ISSN: 1040-0605
eISSN: 1522-1504
DOI Link: https://doi.org/10.1152/ajplung.00232.2013
Verlag: American Physiological Society
Abstract:
In this review we summarize recent major advances in our understanding on the molecular mechanisms, mediators, and biomarkers of acute lung injury (ALI) and alveolar-capillary barrier dysfunction, highlighting the role of immune cells, inflammatory and noninflammatory signaling events, mechanical noxae, and the affected cellular and molecular entities and functions. Furthermore, we address novel aspects of resolution and repair of ALI, as well as putative candidates for treatment of ALI, including pharmacological and cellular therapeutic means.
Zitierstile
Harvard-Zitierstil: Herold, S., Gabrielli, N. and Vadasz, I. (2013) Novel concepts of acute lung injury and alveolar-capillary barrier dysfunction, American Journal of Physiology - Lung Cellular and Molecular Physiology, 305(10), pp. L665-L681. https://doi.org/10.1152/ajplung.00232.2013
APA-Zitierstil: Herold, S., Gabrielli, N., & Vadasz, I. (2013). Novel concepts of acute lung injury and alveolar-capillary barrier dysfunction. American Journal of Physiology - Lung Cellular and Molecular Physiology. 305(10), L665-L681. https://doi.org/10.1152/ajplung.00232.2013
Schlagwörter
alveolar-capillary barrier dysfunction; COLONY-STIMULATING FACTOR; GLYCATION END-PRODUCTS; MESENCHYMAL STEM-CELLS; molecular mechanism; NEUTROPHIL EXTRACELLULAR TRAPS; pharmacological and cell-based therapy; PROVIDING PERMISSIVE HYPERCAPNIA; pulmonary edema; REGULATORY T-CELLS; SODIUM-CHANNEL ACTIVITY; TRANSEPITHELIAL LIQUID TRANSPORT; zaacute lung injury/acute respiratory distress syndrome
