Journal article

Publication year: 2013

Pages: 755-75+

Journal: Ophthalmologe

Volume number: 110

Issue number: 8

ISSN: 0941-293X

eISSN: 1433-0423

DOI Link: https://doi.org/10.1007/s00347-012-2774-x

Publisher: Springer

Abstract: 

Diurnal intraocular pressure (IOP) measurements are recommended in cases of visual field deterioration in glaucoma patients. In this study the rationale of 24 h versus 48 h IOP measurements was investigated.

Mean IOP and maximum IOP values were obtained in 80 patients over a period of 48 h. The IOP measurements (Goldmann tonometry) of day 1 and 2 (taken every 4 h) were compared. To reduce interindividual and intraindividual differences of measurements the statistical calculation took a tolerance level of +/- 2 mmHg and +/- 1 mmHg into account.

Maximum IOP measurements were found to differ between 37.5 % and 65.0% respectively for right eyes and 28.8 % and 47.5% respectively for left eyes depending on the measurement tolerance (+/- 2 mmHg or +/- 1 mmHg) between day 1 and day 2. Mean IOP values were found to differ by 25 % and 51.3 % respectively for right eyes and 26.3 % and 46.3% respectively for left eyes (+/- 2 or +/- 1 mmHg in) between day 1 and day 2. A time-related clustering of extreme deviations could not be found but the maximum values from all patients were found to be roughly equally distributed over daytime and nighttime hours.

Both maximum IOP and mean IOP measurements were found to differ by at least +/- 2 or +/- 1 mmHg between day 1 and 2 at a significant percentage and the maximum values did not peak at a predictable time point during the 48 h. Therefore, 48 h IOP measurements appear to be more reliable than 24 h measurements.

Harvard Citation style: Fischer, N., Weinand, F., Kuegler, M., Scheel, S. and Lorenz, B. (2013) Are diurnal and nocturnal intraocular pressure measurements over 48 h justified?, Ophthalmologe, 110(8), pp. 755-75+. https://doi.org/10.1007/s00347-012-2774-x

APA Citation style: Fischer, N., Weinand, F., Kuegler, M., Scheel, S., & Lorenz, B. (2013). Are diurnal and nocturnal intraocular pressure measurements over 48 h justified?. Ophthalmologe. 110(8), 755-75+. https://doi.org/10.1007/s00347-012-2774-x