Journal article

Beneficial Effects of Residual Right Ventricular Outflow Tract Obstruction on Right Ventricular Volume and Function in Patients After Repair of Tetralogy of Fallot


Authors listLatus, Heiner; Gummel, Kerstin; Rupp, Stefan; Valeske, Klaus; Akintuerk, Hakan; Jux, Christian; Bauer, Juergen; Schranz, Dietmar; Apitz, Christian

Publication year2013

Pages424-430

JournalPediatric Cardiology

Volume number34

Issue number2

ISSN0172-0643

eISSN1432-1971

DOI Linkhttps://doi.org/10.1007/s00246-012-0476-4

PublisherSpringer


Abstract
Preservation of the pulmonary valve, even at the expense of a mild residual stenosis, is the current surgical policy for the management of patients with tetralogy of Fallot (TOF). This study aimed to assess the long-term effect of a residual right ventricular outflow tract obstruction (RVOTO) on RV dimension and function. This study prospectively assessed 53 children (mean age, 13.4 +/- A 6.4 years) after repair of TOF using cardiovascular magnetic resonance imaging. Residual RVOTO on echocardiography was defined as a peak systolic RVOT gradient of 25 mmHg or higher. Patients with RVOTO (n = 29) had significantly less pulmonary regurgitation (25.2 +/- A 10.6 %) than patients without RVOTO (30.8 +/- A 9.3 %; p = 0.05) (n = 24). Compared with patients who had no RVOTO, children with RVOTO had significantly smaller RV end-diastolic volume (94.0 +/- A 2.6 vs 104.0 +/- A 20.7 ml/m(2); p < 0.05) and end-systolic volume (42.9 +/- A 20.0 vs 48.9 +/- A 13.2 ml/m(2); p < 0.05), whereas RV ejection fraction did not differ significantly between the two groups (55.5 +/- A 8.4 vs 54.0 +/- A 6.6 %). Restrictive physiology, assessed by late diastolic forward flow in the main pulmonary artery, was equally distributed within the two groups (31 vs 25 %; nonsignificant difference). According to the study data, residual RVOTO after repair of TOF does not affect RV function, whereas RV dimensions and the degree of pulmonary regurgitation are more favorable in the long-term follow-up evaluation of those patients. These results confirm the beneficial effects of the current strategy for repair of TOF.



Citation Styles

Harvard Citation styleLatus, H., Gummel, K., Rupp, S., Valeske, K., Akintuerk, H., Jux, C., et al. (2013) Beneficial Effects of Residual Right Ventricular Outflow Tract Obstruction on Right Ventricular Volume and Function in Patients After Repair of Tetralogy of Fallot, Pediatric Cardiology, 34(2), pp. 424-430. https://doi.org/10.1007/s00246-012-0476-4

APA Citation styleLatus, H., Gummel, K., Rupp, S., Valeske, K., Akintuerk, H., Jux, C., Bauer, J., Schranz, D., & Apitz, C. (2013). Beneficial Effects of Residual Right Ventricular Outflow Tract Obstruction on Right Ventricular Volume and Function in Patients After Repair of Tetralogy of Fallot. Pediatric Cardiology. 34(2), 424-430. https://doi.org/10.1007/s00246-012-0476-4



Keywords


ANNULUScongenital heart surgeryPRESSURE LOADPulmonary regurgitationPulmonary stenosisPULMONARY VALVE-REPLACEMENTREGURGITATIONSURGICAL REPAIRTetralogy of Fallot

Last updated on 2025-21-05 at 18:39