Journal article
Authors list: Krueger, K.; Wollenhaupt, J.; Albrecht, K.; Alten, R.; Backhaus, M.; Baerwald, C.; Bolten, W.; Braun, J.; Burkhardt, H.; Burmester, G.; Gaubitz, M.; Gause, A.; Gromnica-Ihle, E.; Kellner, H.; Kuipers, J.; Krause, A.; Lorenz, H. -M.; Manger, B.; Nuesslein, H.; Pott, H. -G.; Rubbert-Roth, A.; Schneider, M.; Specker, C.; Schulze-Koops, H.; Tony, H. -P.; Wassenberg, S.; Mueller-Ladner, U.
Publication year: 2012
Pages: 592-59+
Journal: Zeitschrift für Rheumatologie
Volume number: 71
Issue number: 7
ISSN: 0340-1855
eISSN: 1435-1250
DOI Link: https://doi.org/10.1007/s00393-012-1038-0
Publisher: Springer
Abstract:
Following the EULAR recommendations published in 2010 German guidelines for the medical treatment of rheumatoid arthritis were developed based on an update of the systematic literature search and expert consensus. Methotrexate is the standard treatment option at the time of diagnosis, preferably in combination with low dose glucocorticoids. Combined disease-modifying antirheumatic drugs (DMARD) therapy should be considered in patients not responding within 12 weeks. Treatment with biologicals should be initiated in patients with persistent high activity no later than 6 months after conventional treatment and in exceptional situations (e.g. early destruction or unfavorable prognosis) even earlier. If treatment with biologicals remains ineffective, changing to another biological is recommended after 3-6 months. In cases of long-standing remission a controlled reduction of medical treatment can be considered.
Citation Styles
Harvard Citation style: Krueger, K., Wollenhaupt, J., Albrecht, K., Alten, R., Backhaus, M., Baerwald, C., et al. (2012) German 2012 guidelines for the sequential medical treatment of rheumatoid arthritis. Adapted EULAR recommendations and updated treatment algorithm, Zeitschrift für Rheumatologie, 71(7), pp. 592-59+. https://doi.org/10.1007/s00393-012-1038-0
APA Citation style: Krueger, K., Wollenhaupt, J., Albrecht, K., Alten, R., Backhaus, M., Baerwald, C., Bolten, W., Braun, J., Burkhardt, H., Burmester, G., Gaubitz, M., Gause, A., Gromnica-Ihle, E., Kellner, H., Kuipers, J., Krause, A., Lorenz, H., Manger, B., Nuesslein, H., ...Mueller-Ladner, U. (2012). German 2012 guidelines for the sequential medical treatment of rheumatoid arthritis. Adapted EULAR recommendations and updated treatment algorithm. Zeitschrift für Rheumatologie. 71(7), 592-59+. https://doi.org/10.1007/s00393-012-1038-0
Keywords
Biological agents; CLASSIFICATION CRITERIA; COMBINATION THERAPY; Disease-modifying antirheumatic drugs; DOUBLE-BLIND; GOOD INITIAL RESPONSE; LOW DISEASE-ACTIVITY; LOW-DOSE PREDNISOLONE; Medical treatment; METHOTREXATE MONOTHERAPY; MODIFYING ANTIRHEUMATIC DRUGS; RADIOGRAPHIC PROGRESSION
