Journal article

Publication year: 2012

Pages: 224-230

Journal: Zeitschrift für Rheumatologie

Volume number: 71

Issue number: 3

ISSN: 0340-1855

eISSN: 1435-1250

DOI Link: https://doi.org/10.1007/s00393-011-0953-9

Publisher: Springer

Abstract: 
Of all inflammatory rheumatic diseases gout has the highest prevalence. Patients with intermittent acute gout attacks are usually treated by primary care physicians. However, in cases of insufficient long-term control of serum uric acid levels, complications or atypical clinical manifestations may necessitate consultation with a rheumatologist in the further course of the disease. An oligoarticular or polyarticular presentation can give rise to the initial suspicion of rheumatoid or psoriatic arthritis. In these cases a careful clinical work-up supported by laboratory and imaging investigations is necessary and synovial fluid analysis is usually required. As in other rheumatic diseases extra-articular manifestations are of utmost importance for morbidity and mortality. Gout is a complex metabolic and inflammatory disease and besides articular symptoms the renal and cardiovascular effects of hyperuricemia are particularly relevant for the overall prognosis.

Harvard Citation style: Tausche, A., Manger, B., Mueller-Ladner, U. and Schmidt, B. (2012) Gout as a systemic disease. Manifestations, complications and comorbidities of hyperuricaemia, Zeitschrift für Rheumatologie, 71(3), pp. 224-230. https://doi.org/10.1007/s00393-011-0953-9

APA Citation style: Tausche, A., Manger, B., Mueller-Ladner, U., & Schmidt, B. (2012). Gout as a systemic disease. Manifestations, complications and comorbidities of hyperuricaemia. Zeitschrift für Rheumatologie. 71(3), 224-230. https://doi.org/10.1007/s00393-011-0953-9