Journalartikel
Autorenliste: Fransen, Jaap; Johnson, Sindhu R.; van den Hoogen, Frank; Baron, Murray; Allanore, Yannick; Carreira, Patricia E.; Czirjak, Laszlo; Denton, Christopher P.; Distler, Oliver; Furst, Daniel E.; Gabrielli, Armando; Herrick, Ariane; Inanc, Murat; Kahaleh, Bashar; Kowal-Bielecka, Otylia; Medsger, Thomas A., Jr.; Mueller-Ladner, Ulf; Riemekasten, Gabriela; Sierakowski, Stanislaw; Valentini, Gabriele; Veale, Doug; Vonk, Madelon C.; Walker, Ulrich; Chung, Lorinda; Clements, Philip J.; Collier, David H.; Csuka, Mary E.; Jimenez, Sergio; Merkel, Peter A.; Seibold, James R.; Silver, Richard; Steen, Virginia; Tyndall, Alan; Matucci-Cerinic, Marco; Pope, Janet E.; Khanna, Dinesh
Jahr der Veröffentlichung: 2012
Seiten: 351-357
Zeitschrift: Arthritis Care & Research
Bandnummer: 64
Heftnummer: 3
ISSN: 2151-464X
eISSN: 2151-4658
DOI Link: https://doi.org/10.1002/acr.20679
Verlag: Wiley
Objective Classification criteria for systemic sclerosis (SSc; scleroderma) are being updated. Our objective was to select a set of items potentially useful for the classification of SSc using consensus procedures, including the Delphi and nominal group techniques (NGT). Methods. Items were identified through 2 independent consensus exercises performed by the Scleroderma Clinical Trials Consortium and the European League Against Rheumatism Scleroderma Trials and Research Group. The first-round items from both exercises were collated and redundancies were removed, leaving 168 items. A 3-round Delphi exercise was performed using a 1-9 scale (where 1 = completely inappropriate and 9 = completely appropriate) and a consensus meeting using NGT was conducted. During the last Delphi round, the items were ranked on a 1-10 scale. Results. In round 1, 106 experts rated the 168 items. Those with a median score of < 4 were removed, resulting in a list of 102 items. In round 2, the items were again rated for appropriateness and subjected to a consensus meeting using NGT by European and North American SSc experts (n = 16), resulting in 23 items. In round 3, SSc experts (n = 26) then individually scored each of the 23 items in a last Delphi round using an appropriateness score (1-9) and ranking their 10 most appropriate items for the classification of SSc. Presence of skin thickening, SSc-specific autoantibodies, abnormal nailfold capillary pattern, and Raynaud's phenomenon ranked highest in the final list that also included items indicating internal organ involvement. Conclusion. The Delphi exercise and NGT resulted in a set of 23 items for the classification of SSc that will be assessed for their discriminative properties in a prospective study.
Abstract:
Zitierstile
Harvard-Zitierstil: Fransen, J., Johnson, S., van den Hoogen, F., Baron, M., Allanore, Y., Carreira, P., et al. (2012) Items for developing revised classification criteria in systemic sclerosis: Results of a consensus exercise, Arthritis Care & Research, 64(3), pp. 351-357. https://doi.org/10.1002/acr.20679
APA-Zitierstil: Fransen, J., Johnson, S., van den Hoogen, F., Baron, M., Allanore, Y., Carreira, P., Czirjak, L., Denton, C., Distler, O., Furst, D., Gabrielli, A., Herrick, A., Inanc, M., Kahaleh, B., Kowal-Bielecka, O., Medsger, T., Mueller-Ladner, U., Riemekasten, G., Sierakowski, S., ...Khanna, D. (2012). Items for developing revised classification criteria in systemic sclerosis: Results of a consensus exercise. Arthritis Care & Research. 64(3), 351-357. https://doi.org/10.1002/acr.20679
Schlagwörter
ABNORMALITIES; AUTOANTIBODIES; NAILFOLD CAPILLAROSCOPY; PULMONARY ARTERIAL-HYPERTENSION; RAYNAUD PHENOMENON; SCLERODERMA; SUBSETS
