Journalartikel
Autorenliste: Wagenlehner, Florian M. E.; Pilatz, Adrian; Weidner, Wolfgang
Jahr der Veröffentlichung: 2011
Seiten: 51-57
Zeitschrift: International Journal of Antimicrobial Agents
Bandnummer: 38
ISSN: 0924-8579
eISSN: 1872-7913
DOI Link: https://doi.org/10.1016/j.ijantimicag.2011.09.007
Verlag: Elsevier
Urosepsis accounts for approximately 25% of all sepsis cases and may develop from a community-or nosocomial-acquired urinary tract infection (UTI). The underlying UTI is almost exclusively a complicated one with involvement of parenchymatous urogenital organs (e. g. kidneys, prostate). In urosepsis, as in other types of sepsis, the severity of sepsis depends mostly upon the host response. The urological management of urosepsis comprises early diagnosis, early fluid and oxygen treatment, early antibiotic therapy and early control of the complicating factor in the urinary tract. Time from admission to therapy is critical. The shorter the time to effective treatment, the higher is the success rate. This aspect has to become incorporated into the organisational process, including urologists, radiologists and intensive care specialists amongst others. Adequate initial antibiotic therapy has to be insured. This goal implies, however, a wide array of measures over time to ensure a rational antibiotic policy, including microbiologists and clinical pharmacologists. Dosage of an antibiotic in the septic patient generally has to be high to ensure adequate pharmacological exposure in the individual patient. (C) 2011 Elsevier B. V. and the International Society of Chemotherapy. All rights reserved.
Abstract:
Zitierstile
Harvard-Zitierstil: Wagenlehner, F., Pilatz, A. and Weidner, W. (2011) Urosepsis-from the view of the urologist, International Journal of Antimicrobial Agents, 38, pp. 51-57. https://doi.org/10.1016/j.ijantimicag.2011.09.007
APA-Zitierstil: Wagenlehner, F., Pilatz, A., & Weidner, W. (2011). Urosepsis-from the view of the urologist. International Journal of Antimicrobial Agents. 38, 51-57. https://doi.org/10.1016/j.ijantimicag.2011.09.007
Schlagwörter
Antibiotic policy; ANTIMICROBIAL THERAPY; CLINICAL-FEATURES; GRAM-NEGATIVE BACTEREMIA; INTENSIVE-CARE; Obstructive pyelonephritis; PERCUTANEOUS NEPHROLITHOTOMY; Sepsis treatment; SEVERE SEPSIS; SIRS; SPECTRUM-BETA-LACTAMASE; Urinary tract infections; URINARY-TRACT-INFECTIONS; Urosepsis