Journal article

Publication year: 2011

Pages: 454-459

Journal: The Thoracic and Cardiovascular Surgeon

Volume number: 59

Issue number: 8

ISSN: 0171-6425

eISSN: 1439-1902

DOI Link: https://doi.org/10.1055/s-0030-1271028

Publisher: Thieme Publishing / Georg Thieme Verlag

Abstract: 

Introduction: We wanted to answer the question whether biological heart valves are inferior compared to mechanical heart valves in end-stage renal disease (ESRD) patients.

Methods: Between 01/1996 und 12/2006, 44 of 3293 patients undergoing aortic valve replacement (AVR) in a single institution suffered from dialysis-dependent ESRD and underwent a follow-up investigation after 1.9 years (median). Twelve (28.9%) of these patients received a biological, 32 (71.1%) of these patients a mechanical aortic valve prosthesis. To evaluate a possible influence of the valve type (biological/mechanical) on survival, uni- and multivariate logistic regression was used.

Results: ESRD patients after AVR had a relatively poor short-term (30-day mortality: 22.7%) and long-term survival (median survival time: 24.7 months; 95% CI: 0.2-47.7 months), irrespective of the type of heart valve prosthesis (hazard ratio for mortality depending on heart valve type in dialysis patients: 1.31, p = 0.400). Dialysis-dependent patients were not reoperated due to valve-related reasons.

Conclusions: The long-term survival of dialysis-dependent patients after AVR is low (5-year survival: 29.5%) irrespective of the type of heart valve prosthesis. Therefore, the use of biological AVR is not contraindicated in this group of patients.

Harvard Citation style: Boening, A., Boedeker, R., Rosendahl, U., Niemann, B., Haberer, S., Roth, P., et al. (2011) Long-term Results of Mechanical and Biological Heart Valves in Dialysis and Non-Dialysis Patients, The Thoracic and Cardiovascular Surgeon, 59(8), pp. 454-459. https://doi.org/10.1055/s-0030-1271028

APA Citation style: Boening, A., Boedeker, R., Rosendahl, U., Niemann, B., Haberer, S., Roth, P., & Ennker, J. (2011). Long-term Results of Mechanical and Biological Heart Valves in Dialysis and Non-Dialysis Patients. The Thoracic and Cardiovascular Surgeon. 59(8), 454-459. https://doi.org/10.1055/s-0030-1271028