Journal article
Authors list: Wenner, Yaroslava; Wismann, Stephan; Jaeger, Melanie; Pons-Kuehnemann, Joern; Lorenz, Birgit
Publication year: 2011
Pages: 1137-1145
Journal: Graefe's Archive for Clinical and Experimental Ophthalmology
Volume number: 249
Issue number: 8
ISSN: 0721-832X
eISSN: 1435-702X
DOI Link: https://doi.org/10.1007/s00417-011-1630-z
Publisher: Springer
To evaluate in healthy eyes the interchangeability of retinal thickness measurements resulting from different protocols of Spectralis optical coherence tomography (OCT, Heidelberg Engineering, Germany). Three different central volumetric protocols were performed in one session by one single operator in a randomly selected eye of 31 healthy adults (range, 19-30 years): (1) area 6 x 6 mm, 25 scan pattern (SP), (2) area 6 x 6 mm, 49 SP, (3) area 6 x 3 mm, 97 SP. Nine ETDRS areas were analyzed, except outer areas for 97 SP. Interclass correlation coefficients (ICC) and limits of agreement (Bland-Altman) were calculated. Mean minimal foveal thickness was 224.0 +/- 15.8 mu m and central retinal thickness 280.8 +/- 16.5 mu m. ICC ranged from 0.973 to 0.993. Ninety-five percent limits of agreement between the protocols were < 7 mu m in all ETDRS areas. The difference between two measurements never exceeded 9 mu m. Spectralis OCT retinal thickness measurements in healthy subjects showed good protocol interchangeability for all tested protocols. Larger differences are to be expected in eyes with macular pathology.
Abstract:
Citation Styles
Harvard Citation style: Wenner, Y., Wismann, S., Jaeger, M., Pons-Kuehnemann, J. and Lorenz, B. (2011) Interchangeability of macular thickness measurements between different volumetric protocols of Spectralis optical coherence tomography in normal eyes, Graefe's Archive for Clinical and Experimental Ophthalmology, 249(8), pp. 1137-1145. https://doi.org/10.1007/s00417-011-1630-z
APA Citation style: Wenner, Y., Wismann, S., Jaeger, M., Pons-Kuehnemann, J., & Lorenz, B. (2011). Interchangeability of macular thickness measurements between different volumetric protocols of Spectralis optical coherence tomography in normal eyes. Graefe's Archive for Clinical and Experimental Ophthalmology. 249(8), 1137-1145. https://doi.org/10.1007/s00417-011-1630-z
Keywords
Protocol interchangeability; REPEATABILITY; REPRODUCIBILITY; Retinal thickness; RETINAL THICKNESS; Scanning density; SD OCT; Spectral domain optical coherence tomography; TIME-DOMAIN
