Journal article

Multiple ST clonal complexes, with a predominance of ST131, of Escherichia coli harbouring blaCTX-M-15 in a tertiary hospital in Tanzania


Authors listMshana, S. E.; Imirzalioglu, C.; Hain, T.; Domann, E.; Lyamuya, E. F.; Chakraborty, T.

Publication year2011

Pages1279-1282

JournalClinical Microbiology and Infection

Volume number17

Issue number8

ISSN1198-743X

eISSN1469-0691

Open access statusBronze

DOI Linkhttps://doi.org/10.1111/j.1469-0691.2011.03518.x

PublisherElsevier


Abstract
The molecular epidemiology of 32 non-duplicate, CTX-M-15 extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli strains, isolated from clinical samples, was investigated. Multilocus sequence typing revealed multiple sequence type clonal complexes: ST131 (12), ST405 (4), ST638 (3), ST38 (2), ST827 (2), ST224 (1), ST648 (1), ST46 (1) and two new sequence type clonal complexes (1845 and 1848) in 22 pulsed field gel electrophoresis clusters. The bla(CTX-M-15) gene was located on conjugative IncF plasmids. This is the first report of the worldwide emerging clonal complex ST131 linked to bla(CTX-M-15) in Tanzania and demonstrates the need for constant surveillance in developing countries to prevent the spread of these multiresistant isolates.



Citation Styles

Harvard Citation styleMshana, S., Imirzalioglu, C., Hain, T., Domann, E., Lyamuya, E. and Chakraborty, T. (2011) Multiple ST clonal complexes, with a predominance of ST131, of Escherichia coli harbouring blaCTX-M-15 in a tertiary hospital in Tanzania, Clinical Microbiology and Infection, 17(8), pp. 1279-1282. https://doi.org/10.1111/j.1469-0691.2011.03518.x

APA Citation styleMshana, S., Imirzalioglu, C., Hain, T., Domann, E., Lyamuya, E., & Chakraborty, T. (2011). Multiple ST clonal complexes, with a predominance of ST131, of Escherichia coli harbouring blaCTX-M-15 in a tertiary hospital in Tanzania. Clinical Microbiology and Infection. 17(8), 1279-1282. https://doi.org/10.1111/j.1469-0691.2011.03518.x



Keywords


bla(CTX-M-15)CTX-M-15PLASMIDSSPECTRUM BETA-LACTAMASESST131Tanzania

Last updated on 2025-10-06 at 10:01