Journal article

Publication year: 2011

Pages: 271-278

Journal: Zeitschrift für Orthopädie und Unfallchirurgie

Volume number: 149

Issue number: 3

ISSN: 1864-6697

eISSN: 1864-6743

DOI Link: https://doi.org/10.1055/s-0030-1270709

Publisher: Georg Thieme Verlag

Abstract: 

Background: This investigation describes experimental tests of the biomechanical features of a new resorbable bone adhesive based on methacrylate-terminated oligolactides enhanced with osteoconductive beta-tricalcium phosphate.

rabbits were randomised to an adhesive group (n = 29) and a control group (n = 22). An extra-articular bone cylinder was taken from the proximal tibia, two stripes of adhesive were applied and the cylinders were replanted. After 10 and 21 days, 3 and 12 months tibial specimens were harvested and the cylinder pull-out test was performed with a servo-hydraulic machine. Additionally the pull-out force was evaluated with the bone-equivalent Ebazell (R) after 5, 10 and 360 minutes in 14 specimens each.

Results: Average pull-out forces in the adhesive group were 28 N after 10 days (control: 57 N), 155 N after 21 days (216 N), 184 N after 3 months (197 N) and 205 N after 12 months (185 N). Investigations with Ebazell (R) showed almost identical pull-out forces after 5 min, 15 min and 360 min. Adhesive forces were as high as 125 N/cm(2) of adhesive surface and more than 1200 N/g of adhesive mass.

Conclusions: The adhesive investigated here has a very good primary adhesive power, compared to the literature data, achieved after only 5 minutes. Even in moist surroundings the adhesive capacity remains sufficient. The adhesive has to prove its resorptive properties in further investigations and in first line its medium-term and long-lasting biocompatibility. Furthermore, biomechanical features will have to be compared to those of conventional fixation techniques.

Harvard Citation style: Kraus, R., Peters, F., Geck, A., Lips, K., Obert, M., Roeder, C., et al. (2011) Adhesive Strength of a β-Tricalcium Phosphate-Enriched Bone Adhesive, Zeitschrift für Orthopädie und Unfallchirurgie, 149(3), pp. 271-278. https://doi.org/10.1055/s-0030-1270709

APA Citation style: Kraus, R., Peters, F., Geck, A., Lips, K., Obert, M., Roeder, C., Schnabelrauch, M., Schnettler, R., & Heiss, C. (2011). Adhesive Strength of a β-Tricalcium Phosphate-Enriched Bone Adhesive. Zeitschrift für Orthopädie und Unfallchirurgie. 149(3), 271-278. https://doi.org/10.1055/s-0030-1270709