Journal article

The Use of Bone Age in Clinical Practice - Part 2


Authors listMartin, David D.; Wit, Jan M.; Hochberg, Ze'ev; van Rijn, Rick R.; Fricke, Oliver; Werther, George; Cameron, Noel; Hertel, Thomas; Wudy, Stefan A.; Butler, Gary; Thodberg, Hans Henrik; Binder, Gerhard; Ranke, Michael B.

Publication year2011

Pages10-16

JournalHormone Research in Paediatrics

Volume number76

Issue number1

ISSN1663-2818

eISSN1663-2826

Open access statusBronze

DOI Linkhttps://doi.org/10.1159/000329374

PublisherKarger Publishers


Abstract
If height-limiting treatment is being considered for a child with tall stature, skeletal maturity is invaluable in the selection of appropriate patients for treatment, determining appropriate age of treatment commencement, monitoring progress of treatment, and determining the expected treatment effect on adult height. In precocious puberty, bone maturation can be usefully assessed at initial diagnosis and start of treatment and at regular intervals thereafter during treatment monitoring. Together with height, bone maturation is an essential parameter for long-term treatment monitoring in congenital adrenal hyperplasia. Bone age (BA) determination in children with skeletal dysplasia is only feasible in a few disorders and estimations should be treated with caution. Radiographs of the left hand and wrist are, however, essential in the diagnosis of many skeletal disorders. Bone mineralization and measures of bone lengths, width, thickness and cortical thickness should always be evaluated in relation to a child's height and BA, especially around puberty. The use of skeletal maturity, assessed on a radiograph alone to estimate chronological age for immigration authorities or criminal courts is not recommended. Copyright (C) 2011 S. Karger AG, Basel



Citation Styles

Harvard Citation styleMartin, D., Wit, J., Hochberg, Z., van Rijn, R., Fricke, O., Werther, G., et al. (2011) The Use of Bone Age in Clinical Practice - Part 2, Hormone Research in Paediatrics, 76(1), pp. 10-16. https://doi.org/10.1159/000329374

APA Citation styleMartin, D., Wit, J., Hochberg, Z., van Rijn, R., Fricke, O., Werther, G., Cameron, N., Hertel, T., Wudy, S., Butler, G., Thodberg, H., Binder, G., & Ranke, M. (2011). The Use of Bone Age in Clinical Practice - Part 2. Hormone Research in Paediatrics. 76(1), 10-16. https://doi.org/10.1159/000329374



Keywords


21-HYDROXYLASE DEFICIENCYbone ageBone mineral densityCENTRAL PRECOCIOUS PUBERTYCongenital adrenal hyperplasiaCONGENITAL ADRENAL-HYPERPLASIAESTROGEN-TREATMENTFINAL HEIGHTPrecocious pubertyPREDICTED ADULT HEIGHTSkeletal maturitySKELETAL MATURITYTall statureTALL STATURE

Last updated on 2025-10-06 at 10:01