Journalartikel

Jahr der Veröffentlichung: 2011

Seiten: 177-182

Zeitschrift: Annals of Nutrition and Metabolism

Bandnummer: 57

Heftnummer: 3-4

ISSN: 0250-6807

DOI Link: https://doi.org/10.1159/000321538

Verlag: Karger Publishers

Abstract: 
Background: The factors influencing total plasma homocysteine levels (tHcy) are of special interest in the attempt to reduce cardiovascular risk. Aim: This investigation aimed to assess the independent effects of antioxidant vitamins on tHcy in elderly people. Methods: Our cross-sectional analysis included data of 184 subjects (>= 60 years) from the longitudinal study in an aging population in Giessen (GISELA), Germany. We examined the effects of plasma levels, intake and supplementation of vitamin C, vitamin E, and beta-carotene on tHcy. Results: The mean tHcy was within the normal range in this population. Serum folate, the estimated glomerular filtration rate (eGFR), and plasma vitamin C showed a negative association with tHcy in simple regression analysis. In a subsequent multiple regression analysis, eGFR, serum folate, and plasma vitamin C were the relevant independent predictors of tHcy. Intake and supplementation of vitamin C, as well as plasma levels, intake and supplementation of vitamin E, and beta-carotene were not associated with tHcy. Conclusion: Vitamin C may be an independent predictor of tHcy in free-living elderly people and, therefore, should be considered in attempts to reduce tHcy. Copyright (C) 2010 S. Karger AG, Basel

Harvard-Zitierstil: Breilmann, J., Pons-Kuehnemann, J., Brunner, C., Richter, M. and Neuhaeuser-Berthold, M. (2011) Effect of Antioxidant Vitamins on the Plasma Homocysteine Level in a Free-Living Elderly Population, Annals of Nutrition and Metabolism, 57(3-4), pp. 177-182. https://doi.org/10.1159/000321538

APA-Zitierstil: Breilmann, J., Pons-Kuehnemann, J., Brunner, C., Richter, M., & Neuhaeuser-Berthold, M. (2011). Effect of Antioxidant Vitamins on the Plasma Homocysteine Level in a Free-Living Elderly Population. Annals of Nutrition and Metabolism. 57(3-4), 177-182. https://doi.org/10.1159/000321538