Journal article

Publication year: 2011

Pages: 29-36

Journal: Ultrasound in Medicine and Biology

Volume number: 37

Issue number: 1

ISSN: 0301-5629

eISSN: 1879-291X

Open access status: Bronze

DOI Link: https://doi.org/10.1016/j.ultrasmedbio.2010.10.003

Publisher: Elsevier

Abstract: 
The ability of spinal dual x-ray absorptiometry (DXA), calcaneal quantitative ultrasound (QUS) and spinal quantitative computed tomography (QCT) to identify women with osteoporosis within the GISELA study was evaluated in 43 women, aged 62-87 years. Osteoporosis was defined as a T-score below or equal to -2.5 using DXA (femoral neck). To determine the performance of each method, the sensitivity, specificity and area under the curve (by means of a receiver operating characteristic [ROC] analysis) were calculated. The median T-scores from the measurements differed significantly (p < 0.0001). DXA (spine) identified 75% of women with osteoporosis; QUS and QCT identified 100%. The specificity was 89% for DXA (spine), 66% for QUS and 29% for QCT. ROC analysis showed that all three methods are qualified to identify women with osteoporosis; however, the different sensitivities and specificities of the methods, as well as the thresholds used for diagnosing osteoporosis have to be considered. (E-mail: monika.neuhaeuser-berthold@ernaehrung.uni-giessen.de) (C) 2011 Published by Elsevier Inc. on behalf of World Federation for Ultrasound in Medicine & Biology.

Harvard Citation style: Edelmann-Schaefer, B., Berthold, L., Stracke, H., Luehrmann, P. and Neuhaeuser-Berthold, M. (2011) IDENTIFYING ELDERLY WOMEN WITH OSTEOPOROSIS BY SPINAL DUAL X-RAY ABSORPTIOMETRY, CALCANEAL QUANTITATIVE ULTRASOUND AND SPINAL QUANTITATIVE COMPUTED TOMOGRAPHY: A COMPARATIVE STUDY, Ultrasound in Medicine and Biology, 37(1), pp. 29-36. https://doi.org/10.1016/j.ultrasmedbio.2010.10.003

APA Citation style: Edelmann-Schaefer, B., Berthold, L., Stracke, H., Luehrmann, P., & Neuhaeuser-Berthold, M. (2011). IDENTIFYING ELDERLY WOMEN WITH OSTEOPOROSIS BY SPINAL DUAL X-RAY ABSORPTIOMETRY, CALCANEAL QUANTITATIVE ULTRASOUND AND SPINAL QUANTITATIVE COMPUTED TOMOGRAPHY: A COMPARATIVE STUDY. Ultrasound in Medicine and Biology. 37(1), 29-36. https://doi.org/10.1016/j.ultrasmedbio.2010.10.003