Journal article

Reassessing the Standard of Care in Indolent Lymphoma: A Clinical Update to Improve Clinical Practice


Authors listRummel, Mathias

Publication year2010

PagesS1-S15

JournalJournal of the National Comprehensive Cancer Network

Volume number8

ISSN1540-1405

PublisherJones and Bartlett


Abstract
Non-Hodgkin's lymphoma (NHL) represents a diverse group of hematologic malignancies originating in B or T lymphocytes. Approximately 85% of NHLs are of B-cell origin, with the remainder mostly of T-cell origin. The most common NHL types are diffuse large B-cell lymphoma (31%) and follicular lymphoma (22%). More than 65,000 new cases of NHL develop each year, and approximately 20,000 people with NHL died of the disease 2009. NHL is the seventh most common cancer in the United States, contributes to approximately 4% to 5% of all cancer cases in the United States, and causes approximately 3% of all cancer-related deaths. Currently, nearly 500,000 people are living with the disease or are in remission. Several new and encouraging advances have been made in the treatment of indolent NHL. Although the watch and wait approach still has a role, combined immunochemotherapy remains the standard of care for both first-line and relapsed/refractory disease. As front-line treatment, bendamustine plus rituximab may become a new standard of care, especially for older patients. In contrast, rituximab in combination with chemotherapy followed by rituximab maintenance seems to be the optimal option in patients with relapsed disease. (JNCCN 2010;8[Suppl 6]:S1 S14)



Citation Styles

Harvard Citation styleRummel, M. (2010) Reassessing the Standard of Care in Indolent Lymphoma: A Clinical Update to Improve Clinical Practice, Journal of the National Comprehensive Cancer Network, 8, pp. S1-S15

APA Citation styleRummel, M. (2010). Reassessing the Standard of Care in Indolent Lymphoma: A Clinical Update to Improve Clinical Practice. Journal of the National Comprehensive Cancer Network. 8, S1-S15.



Keywords


Chronic lymphocytic leukemiaCHRONIC LYMPHOCYTIC-LEUKEMIACLLdiffuse large B-cell lymphomaFLUDARABINE PLUS CYCLOPHOSPHAMIDEFOLLICULAR LYMPHOMAMANTLE-CELL LYMPHOMANHLNon-Hodgkin's lymphomaNON-HODGKINS-LYMPHOMAPHASE-III TRIALPROGRESSION-FREE SURVIVALRITUXIMAB MAINTENANCESLLsmall lymphocytic lymphomaUNTREATED PATIENTSWALDENSTROM MACROGLOBULINEMIAWaldenstrom's macroglobulinemia

Last updated on 2025-21-05 at 18:42