Journal article

A regenerative strategy for heart failure in hypoplastic Left heart syndrome: Intracoronary administration of autologous bone marrow-derived progenitor cells


Authors listRupp, Stefan; Zeiher, Andreas M.; Dimmeler, Stefanie; Tonn, Torsten; Bauer, Juergen; Jux, Christian; Akintuerk, Hakan; Schranz, Dietmar

Publication year2010

Pages574-577

JournalThe Journal of Heart and Lung Transplantation

Volume number29

Issue number5

ISSN1053-2498

eISSN1557-3117

DOI Linkhttps://doi.org/10.1016/j.healun.2009.10.006

PublisherElsevier


Abstract
Novel surgical strategies have dramatically improved the initial outcome of newborns with hypoplastic left heart syndrome. However, the single systemic right ventricle remains a major challenge, with limited effectiveness of pharmacologic therapy. The present case documents that the intracoronary administration of autologous bone marrow-derived progenitor cells is technically feasible in a critically ill infant with hypoplastic left heart syndrome and severe heart failure after a hybrid comprehensive stage II procedure. Cell therapy might represent an option before heart transplantation in children with single ventricle physiology presenting with severe heart failure. J Heart Lung Transplant 2010;29:574-577 (C) 2010 International Society for Heart and Lung Transplantation. All rights reserved.



Citation Styles

Harvard Citation styleRupp, S., Zeiher, A., Dimmeler, S., Tonn, T., Bauer, J., Jux, C., et al. (2010) A regenerative strategy for heart failure in hypoplastic Left heart syndrome: Intracoronary administration of autologous bone marrow-derived progenitor cells, The Journal of Heart and Lung Transplantation, 29(5), pp. 574-577. https://doi.org/10.1016/j.healun.2009.10.006

APA Citation styleRupp, S., Zeiher, A., Dimmeler, S., Tonn, T., Bauer, J., Jux, C., Akintuerk, H., & Schranz, D. (2010). A regenerative strategy for heart failure in hypoplastic Left heart syndrome: Intracoronary administration of autologous bone marrow-derived progenitor cells. The Journal of Heart and Lung Transplantation. 29(5), 574-577. https://doi.org/10.1016/j.healun.2009.10.006



Keywords


ACUTE MYOCARDIAL-INFARCTIONautologous stem cell therapyCARDIAC REPAIRHLHSTRANSPLANTATION

Last updated on 2025-21-05 at 18:42