Journal article
Authors list: Lambova, Sevdalina Nikolova; Mueller-Ladner, Ulf
Publication year: 2009
Pages: 1263-1271
Journal: Rheumatology International
Volume number: 29
Issue number: 11
ISSN: 0172-8172
eISSN: 1437-160X
DOI Link: https://doi.org/10.1007/s00296-009-1019-z
Publisher: Springer
Abstract:
The purpose of this study is to study and systematize the current knowledge about the role of capillaroscopy in differentiation of primary and secondary Raynaud's phenomenon (RP) in rheumatic diseases. This method is a review of the literature. Capillaroscopy is of crucial value for diagnosis and differentiation of primary and secondary RP in rheumatic diseases. The appearance of abnormal capillaroscopic pattern inherits high positive predictive value for the development of systemic rheumatic disease. The most specific pattern is found in systemic sclerosis (SSc), so called "scleroderma pattern", which is characterized by the presence of dilated capillaries, hemorrhages, avascular areas and neoangiogeneis. It is found in more than 90% of patients with overt SSc. Similar changes are found in patients with dermatomyositis, mixed connective tissue disease, undifferentiated connective tissue disease and they are called "scleroderma-like pattern". Absence of abnormal capillaroscopic findings can be regarded as a diagnostic criterion for primary RP. Inclusion of pathologic capillaroscopic pattern may increase the sensitivity of ACR classification criteria for SSc. In conclusion, capillaroscopy is of crucial importance for the differentiation of primary and secondary RP in rheumatic diseases, and also in differentiation between different forms of connective tissue diseases as well as for their early diagnosis.
Citation Styles
Harvard Citation style: Lambova, S. and Mueller-Ladner, U. (2009) The role of capillaroscopy in differentiation of primary and secondary Raynaud's phenomenon in rheumatic diseases: a review of the literature and two case reports, Rheumatology International, 29(11), pp. 1263-1271. https://doi.org/10.1007/s00296-009-1019-z
APA Citation style: Lambova, S., & Mueller-Ladner, U. (2009). The role of capillaroscopy in differentiation of primary and secondary Raynaud's phenomenon in rheumatic diseases: a review of the literature and two case reports. Rheumatology International. 29(11), 1263-1271. https://doi.org/10.1007/s00296-009-1019-z
Keywords
antiphospholipid syndrome; Capillaroscopy; CLASSIFICATION CRITERIA; CONNECTIVE-TISSUE DISEASE; MICROVASCULAR ABNORMALITIES; NAILFOLD VIDEOCAPILLAROSCOPIC PATTERNS; PRIMARY SJOGRENS-SYNDROME; Raynaud's phenomenon; Rheumatic diseases; SCLERODERMA SPECTRUM DISORDERS; SYSTEMIC-LUPUS-ERYTHEMATOSUS; VASCULAR-DISEASE; VIDEO CAPILLAROSCOPY
