Journal article

Publication year: 2009

Pages: 677-679

Journal: Pediatric Blood & Cancer

Volume number: 52

Issue number: 5

ISSN: 1545-5009

DOI Link: https://doi.org/10.1002/pbc.21920

Publisher: Wiley

Abstract: 
We report a 12-year-old female presenting with in abdominal tumor. Diagnostic workup revealed giant bilateral ovarian cysts, severe hypothyroidism as well as an elevation of CA 125. We refrained from ovariectomy, which would be necessary for a malignant tumor, in view of an evident Van Wyk and Grumbach syndrome. The patient promptly responded to 1-thyroxine with complete regression of all symptoms. Hypothyroidism should be considered in the evaluation of ovarian cysts. Although the Van Wyk and Grumbach syndrome is rare, it is crucial to rule it out in order to avoid unnecessary ovarian surgery when thyroid replacement is completely sufficient. Pediatr Blood Cancer 2009;52:677-679. (C) 2009 Wiley-Liss, Inc.

Harvard Citation style: Hunold, A., Alzen, G., Wudy, S., Bluetters-Sawatzki, R., Landmann, E., Reiter, A., et al. (2009) Ovarian Tumor in a 12-Year Old Female With Severe Hypothyroidism: A Case of Van Wyk and Grumbach Syndrome, Pediatric Blood & Cancer, 52(5), pp. 677-679. https://doi.org/10.1002/pbc.21920

APA Citation style: Hunold, A., Alzen, G., Wudy, S., Bluetters-Sawatzki, R., Landmann, E., Reiter, A., & Wagner, H. (2009). Ovarian Tumor in a 12-Year Old Female With Severe Hypothyroidism: A Case of Van Wyk and Grumbach Syndrome. Pediatric Blood & Cancer. 52(5), 677-679. https://doi.org/10.1002/pbc.21920