Journalartikel
Autorenliste: Preissner, K. T.
Jahr der Veröffentlichung: 2008
Seiten: 259-25+
Zeitschrift: Hämostaseologie
Bandnummer: 28
Heftnummer: 5
ISSN: 0720-9355
Verlag: Thieme Publishing
Abstract:
The principles of initiator and amplifications reactions of blood coagulation and fibrinolysis will be presented and discussed in relation to various regulatory pathways of haemostasis. In particular, cell surface-dependent activation and inhibition reactions are characteristics of multicomponent enzyme complexes that also allow the endogenous control of the haemostasis system. The understanding of these relationships in complications of haemostasis has lead to different strategies for the therapeutic intervention with pro- and anticoagulant substances.
Zitierstile
Harvard-Zitierstil: Preissner, K. (2008) Physiology of blood coagulation and fibrinolysis Biochemistry, Hämostaseologie, 28(5), pp. 259-25+
APA-Zitierstil: Preissner, K. (2008). Physiology of blood coagulation and fibrinolysis Biochemistry. Hämostaseologie. 28(5), 259-25+.
Schlagwörter
ACTIVATED PROTEIN-C; enzyme cascade; gene defects; HEMOSTASIS; Multicomponent enzyme complexes; surface reactions; THROMBIN; THROMBOMODULIN; THROMBOSIS; TISSUE FACTOR PATHWAY; VENOUS THROMBOEMBOLISM; VESSEL