Conference paper

Expression and function of ETA and ETB receptors in SSc


Authors listFrommer, K. W.; Mueller-Ladner, U.

Publication year2008

PagesV27-V28

JournalRheumatology

Volume number47

ISSN1462-0324

eISSN1462-0332

Open access statusGreen

DOI Linkhttps://doi.org/10.1093/rheumatology/ken274

ConferenceSymposium on Controversies in Scleroderma

PublisherOxford University Press


Abstract
Endothelin (ET) receptors are widely expressed within the human body with one of their major functions being regulation of the vascular tone. Pulmonary arterial hypertension and other complications associated with SSc are related to the function and or dysregulation of these receptors. As ET receptors also play a crucial role in SSc, this review will discuss the expression and physiological functions of ET receptors in the human organism, their signalling pathways, the complications of diseases they are associated with and their importance as a therapeutic target in SSc.



Citation Styles

Harvard Citation styleFrommer, K. and Mueller-Ladner, U. (2008) Expression and function of ETA and ETB receptors in SSc, Rheumatology, 47, pp. V27-V28. https://doi.org/10.1093/rheumatology/ken274

APA Citation styleFrommer, K., & Mueller-Ladner, U. (2008). Expression and function of ETA and ETB receptors in SSc. Rheumatology. 47, V27-V28. https://doi.org/10.1093/rheumatology/ken274



Keywords


EndothelinEndothelin(A) receptorsEndothelin(B) receptorsENDOTHELIN RECEPTORSfunctionSCLERODERMASystemic sclerosis

Last updated on 2025-10-06 at 09:50