Journal article

Autoinimune hepatitis after high-dose intravenous methylprednisolone pulse in RR-MS


Authors listReuss, Reinhard; Retzlaff, Kerstin; Vogel, Sabine; Franke, Folker Ernst; Oschmann, Patrick

Publication year2007

Pages356-359

JournalCentral European Journal of Medicine

Volume number2

Issue number3

ISSN1895-1058

Open access statusHybrid

DOI Linkhttps://doi.org/10.2478/s11536-007-0025-3

PublisherSpringer Verlag


Abstract
Three weeks after the administration of intravenous methylprednisolone therapy, a 42-year-old female patient suffering from relapsinog-remitting multiple sclerosis (RR-MS) presented with a profound elevation of liver transaminases (GOT 485 U/1, GPT 1082 U/1, glutamyl transpeptidase 170 U/1). Liver biopsy revealed a profound, still active hepatitis with portal lymphocytic infiltration and fibrosis. Most likely, existing acute hepatitis was of autoinimune origin and emerged from an immune rebound phenomenon after immunosuppressive therapy. (c) Versita Warsaw and Sprinaer-Verlag Berlin Heidelberg. All rights reserved.



Citation Styles

Harvard Citation styleReuss, R., Retzlaff, K., Vogel, S., Franke, F. and Oschmann, P. (2007) Autoinimune hepatitis after high-dose intravenous methylprednisolone pulse in RR-MS, Central European Journal of Medicine, 2(3), pp. 356-359. https://doi.org/10.2478/s11536-007-0025-3

APA Citation styleReuss, R., Retzlaff, K., Vogel, S., Franke, F., & Oschmann, P. (2007). Autoinimune hepatitis after high-dose intravenous methylprednisolone pulse in RR-MS. Central European Journal of Medicine. 2(3), 356-359. https://doi.org/10.2478/s11536-007-0025-3



Keywords


AUTOIMMUNE HEPATITISmethylprednisolonemultiple sclerosisOPHTHALMOPATHYrebound phenomenontransaminases

Last updated on 2025-19-08 at 16:06