Journalartikel
Autorenliste: Lucas, Rudolf; Hundsberger, Harald; Pflueger, Maren; Fischer, Bernhard; Morel, Denis; Braun, Clemens; Wendel, Albrecht; Chakraborty, Trinad; Schuett, Wolfgang; Wiesner, Christoph; Hamacher, Juerg
Jahr der Veröffentlichung: 2007
Seiten: 336-340
Zeitschrift: Letters in Drug Design & Discovery
Bandnummer: 4
Heftnummer: 5
ISSN: 1570-1808
eISSN: 1875-628X
DOI Link: https://doi.org/10.2174/157018007780867816
Verlag: Bentham Science Publishers
Abstract:
In view of the significant side-effects of existing substances as well as of supportive therapies for the treatment of pulmonary edema, there is a renewed search for novel drugs that increase the uptake of sodium in type II alveolar epithelial cells, a phenomenon which is crucial for lung liquid clearance. We describe here the discovery and characterization of a Tumor Necrosis Factor (TNF)-derived peptide mimicking the lectin-like domain of the cytokine as a potential novel anti-edema agent.
Zitierstile
Harvard-Zitierstil: Lucas, R., Hundsberger, H., Pflueger, M., Fischer, B., Morel, D., Braun, C., et al. (2007) The tumor necrosis factor-derived TIP peptide:: A potential anti-edema drug, Letters in Drug Design & Discovery, 4(5), pp. 336-340. https://doi.org/10.2174/157018007780867816
APA-Zitierstil: Lucas, R., Hundsberger, H., Pflueger, M., Fischer, B., Morel, D., Braun, C., Wendel, A., Chakraborty, T., Schuett, W., Wiesner, C., & Hamacher, J. (2007). The tumor necrosis factor-derived TIP peptide:: A potential anti-edema drug. Letters in Drug Design & Discovery. 4(5), 336-340. https://doi.org/10.2174/157018007780867816
Schlagwörter
acute lung injury; ADHESION MOLECULE EXPRESSION; ALVEOLAR FLUID CLEARANCE; FACTOR-ALPHA; Lectin; pulmonary edema; sodium channels; TAMM-HORSFALL GLYCOPROTEIN; TNF
