Journalartikel

Jahr der Veröffentlichung: 2007

Seiten: 446-450

Zeitschrift: Der Orthopäde

Bandnummer: 36

Heftnummer: 5

ISSN: 0085-4530

eISSN: 1433-0431

DOI Link: https://doi.org/10.1007/s00132-007-1084-5

Verlag: Springer

Abstract: 
Avascular necrosis (AVN) of the hip is one of the unsolved problems in orthopedics, especially with regard to drug therapy. Only a few studies exist using a long-term approach with vasodilating agents such as prostaglandins, anticoagulants, hormones, as well as lipid lowering and bone protective drugs such as bisphosphonates. However, using these medications several studies have demonstrated a significant reduction in pain, in the destruction of the femoral head as well as in overall disability. This resulted in a reduced need for joint replacement in patients with AVN and to a substantial improvement in quality of life. Of note, drug therapy should be initiated in the early phases of AVN as later stages appear to be less responsive to medication.

Harvard-Zitierstil: Tarner, I., Dinser, R. and Mueller-Ladner, U. (2007) Pharmacotherapeutic aspects of femoral head necrosis, Orthopäde, 36(5), pp. 446-450. https://doi.org/10.1007/s00132-007-1084-5

APA-Zitierstil: Tarner, I., Dinser, R., & Mueller-Ladner, U. (2007). Pharmacotherapeutic aspects of femoral head necrosis. Orthopäde. 36(5), 446-450. https://doi.org/10.1007/s00132-007-1084-5