Journal article

Publication year: 2007

Pages: 732-735

Journal: Movement Disorders

Volume number: 22

Issue number: 5

ISSN: 0885-3185

eISSN: 1531-8257

DOI Link: https://doi.org/10.1002/mds.21338

Publisher: Wiley

Abstract: 
This is a single case report of a patient with spinocerebellar ataxia type 2 (SCA2) and severe tremor. Whereas disease progression with prevailing ataxia and dysmetria was slow over the first symptomatic 6 years, 6 months prior to operation were characterized by the development of a severe, debilitating postural tremor rendering the patient unable to independently sit, stand, speak, or swallow. Deep brain stimulation (DBS) at a subthalamic-thalamic electrode position almost completely arrested her tremor. The patient regained the functional state prior to her rapid disease progression allowing a restricted range of daily activities. Her condition has remained approximately stable over the two postoperative years to date. In addition to the efficacy of DBS on cerebellar tremor, the results illustrate a remarkable improvement of the patient's general condition and independence. (c) 2007 Movement Disorder Society.

Harvard Citation style: Freund, H., Barnikol, U., Nolte, D., Treuer, H., Auburger, G., Tass, P., et al. (2007) Subthalamic-thalamic DBS in a case with spinocerebellar ataxia type 2 and severe tremor - A unusual clinical benefit, Movement Disorders, 22(5), pp. 732-735. https://doi.org/10.1002/mds.21338

APA Citation style: Freund, H., Barnikol, U., Nolte, D., Treuer, H., Auburger, G., Tass, P., Samii, M., & Sturm, V. (2007). Subthalamic-thalamic DBS in a case with spinocerebellar ataxia type 2 and severe tremor - A unusual clinical benefit. Movement Disorders. 22(5), 732-735. https://doi.org/10.1002/mds.21338